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Product details

Chromogranin A Mouse Monoclonal Antibody [A3H1]

Catalog number HA600016

Price for HA600016

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Size / count 100 µL

About this product

Strongly inhibits glucose induced insulin release from the pancreas.Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, and Gram-negative bacteria E.coli and P.aeruginosa . Can induce mast cell migration, degranulation and production of cytokines and chemokines . Acts as a potent scavenger of free radicals in vitro tion and blood pressure .Regulates granule biogenesis in endocrine cells by up-regulating the transcription of protease nexin 1 (SERPINE2) via a cAMP-PKA-SP1 pathway. This leads to inhibition of granule protein degradation in the Golgi complex which in turn promotes granule formation.

Specifications

Catalog number
HA600016
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
beta Granin antibody betagranin (N-terminal fragment of chromogranin A) antibody catestatin antibody CgA antibody CHG A antibody Chga antibody chromofungin antibody Chromogranin A antibody Chromogranin A parathyroid secretory protein 1 antibody Chromogranin A precursor antibody ChromograninA antibody CMGA_HUMAN antibody ER-37 antibody Pancreastatin antibody Parastatin antibody Parathyroid secretory protein 1 antibody Pituitary secretory protein I antibody Secretory protein I antibody SP I antibody SP-I antibody SP1 antibody SPI antibody vasostatin 2 antibody Vasostatin antibody Vasostatin I antibody Vasostatin II antibody vasostatin-2 antibody
Abbreviation
CHGA
Swiss Prot
P10645 Human, P26339 Mouse, P10354 Rat
Cellular Locus
Cytoplasmic vesicle, Secreted.
Host
Mouse
Species Reactivity
Human, Mouse, Rat
Immunogen
Recombinant protein within human Chromogranin A aa 358-457.
Isotype
IgG
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IHC-P
Positive Control
PC-12 cell lysates, mouse kidney tissue lysate, human small intestine tissue lysate, human pancreas tissue, rat pancreas tissue, mouse pancreas tissue, human medullary thyroid carcinoma tissue, human atypical carcinoid tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:100-1:2,000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 51 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Chromogranin A Mouse Monoclonal Antibody [A3H1]?

The catalog number for Chromogranin A Mouse Monoclonal Antibody [A3H1] is HA600016.

What sizes are available for Chromogranin A Mouse Monoclonal Antibody [A3H1]?

Chromogranin A Mouse Monoclonal Antibody [A3H1] is available in the following size(s): 100 µL.

Is Chromogranin A Mouse Monoclonal Antibody [A3H1] in stock?

Chromogranin A Mouse Monoclonal Antibody [A3H1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Chromogranin A Mouse Monoclonal Antibody [A3H1] used for?

Strongly inhibits glucose induced insulin release from the pancreas.Inhibits catecholamine release from chromaffin cells and noradrenergic neurons by acting as a non-competitive nicotinic cholinergic antagonist. Displays antibacterial activity against Gram-positive bacteria S.aureus and M.luteus, an

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

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