PCBP1 Mouse Monoclonal Antibody [A3E10]

About this product

This intronless gene is thought to have been generated by retrotransposition of a fully processed PCBP-2 mRNA. This gene and PCBP-2 have paralogues (PCBP3 and PCBP4) which are thought to have arisen as a result of duplication events of entire genes. The protein encoded by this gene appears to be multifunctional. It along with PCBP2 and HNRNPK corresponds to the major cellular poly (rC)-binding protein. It contains three K-homologous (KH) domains which may be involved in RNA binding. This encoded protein together with PCBP-2 also functions as translational coactivators of poliovirus RNA via a sequence-specific interaction with stem-loop IV of the IRES and promote poliovirus RNA replication by binding to its 5'-terminal cloverleaf structure.

Specifications

Catalog number

HA600019

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

Alpha-CP1 antibody Heterogeneous nuclear ribonucleoprotein E1 antibody heterogenous nuclear ribonucleoprotein E1 antibody heterogenous nuclear ribonucleoprotein X antibody hnRNP E1 antibody hnRNP-E1 antibody hnRNP-X antibody HNRPE1 antibody HNRPX antibody nucleic acid binding protein sub 2.3 antibody Nucleic acid- binding protein SUB2.3 antibody Nucleic acid-binding protein SUB2.3 antibody PCBP1 antibody PCBP1_HUMAN antibody poly (rC) binding protein 1 antibody Poly (rC)-binding protein 1 antibody rCbinding protein 1 antibody

Abbreviation

Poly (rC)-binding protein 1 Alpha-CP1 Heterogeneous nuclear ribonucleoprotein E1 hnRNP E1 Nucleic acid-binding protein SUB2.3

Swiss Prot

Q15365 Human, P60335 Mouse

Cellular Locus

Cytoplasm, Nucleus.

Host

Mouse

Species Reactivity

Human, Mouse

Immunogen

Recombinant protein within human PCBP1 aa 1-356.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Hela cell lysate, K562 cell lysate, Human colon cancer tissue.

Concentration

2 mg/mL

Dilution

WB: 1:2,000-1:5,000 ;IHC-P: 1:100-1:500

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

37 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No