FEN1 Mouse Monoclonal Antibody [A1B12] — image 1 of 3

Product details

FEN1 Mouse Monoclonal Antibody [A1B12]

Catalog number HA600025

Price for HA600025

Size / count 100 µL

About this product

The protein encoded by this gene removes 5' overhanging flaps in DNA repair and processes the 5' ends of Okazaki fragments in lagging strand DNA synthesis. Direct physical interaction between this protein and AP endonuclease 1 during long-patch base excision repair provides coordinated loading of the proteins onto the substrate, thus passing the substrate from one enzyme to another. The protein is a member of the XPG/RAD2 endonuclease family and is one of ten proteins essential for cell-free DNA replication. DNA secondary structure can inhibit flap processing at certain trinucleotide repeats in a length-dependent manner by concealing the 5' end of the flap that is necessary for both binding and cleavage by the protein encoded by this gene. Therefore, secondary structure can deter the protective function of this protein, leading to site-specific trinucleotide expansions.

Specifications

Catalog number: HA600025
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: DNase IV antibody FEN-1 antibody FEN1 antibody FEN1_HUMAN antibody Flap endonuclease 1 antibody Flap structure specific endonuclease 1 antibody Flap structure-specific endonuclease 1 antibody hFEN-1 antibody hFEN1 antibody Maturation factor 1 antibody MF1 antibody Rad2 antibody
Abbreviation: FEN1
Swiss Prot: P39748 Human, P39749 Mouse, Q5XIP6 Rat
Cellular Locus: Nucleolus, nucleoplasm. Mitochondrion.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human FEN1 aa 150-380.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: MCF-7 cell lysate, K562 cell lysate, Daudi cell lysate, PC-12 cell lysate, NIH/3T3 cell lysate, human tonsil tissue, human liver carcinoma tissue, human breast carcinoma tissue, K562.
Concentration: 2 mg/mL
Dilution: WB:1:500-1:2,000 ;IHC-P:1:100-1:500 ;FC:1:50-1:100
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 1% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 43 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for FEN1 Mouse Monoclonal Antibody [A1B12]?

The catalog number for FEN1 Mouse Monoclonal Antibody [A1B12] is HA600025.

What sizes are available for FEN1 Mouse Monoclonal Antibody [A1B12]?

FEN1 Mouse Monoclonal Antibody [A1B12] is available in the following size(s): 100 µL.

Is FEN1 Mouse Monoclonal Antibody [A1B12] in stock?

FEN1 Mouse Monoclonal Antibody [A1B12] is currently made to order / not held in immediate stock. Contact us for lead time.

What is FEN1 Mouse Monoclonal Antibody [A1B12] used for?

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.