Pan-Actin Mouse Monoclonal Antibody [A2E1]

About this product

Actins are highly conserved proteins that are involved in various types of cell motility and are ubiquitously expressed in all eukaryotic cells. ACTC1 encodes cardiac muscle alpha actin. This isoform differs from the alpha actin that is expressed in skeletal muscle, ACTA1. Alpha cardiac actin is the major protein of the thin filament in cardiac sarcomeres, which are responsible for muscle contraction and generation of force to support the pump function of the heart. ACTA2 (actin alpha 2) is an actin protein with several aliases including alpha-actin, alpha-actin-2, aortic smooth muscle or alpha smooth muscle actin (α-SMA, SMactin, alpha-SM-actin, ASMA). Actins are a family of globular multi-functional proteins that form microfilaments. ACTA2 is one of 6 different actin isoforms and is involved in the contractile apparatus of smooth muscle. ACTA2 (as with all the actins) is extremely highly conserved and found in nearly all mammals. Actin, alpha skeletal muscle is a protein that in humans is encoded by the ACTA1 gene. Actin alpha 1 which is expressed in skeletal muscle is one of six different actin isoforms which have been identified. Actins are highly conserved proteins that are involved in cell motility, structure and integrity. Alpha actins are a major constituent of the contractile apparatus.

Specifications

Catalog number

HA600032

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

a actin antibody ACTA antibody ACTA1 antibody Actin, alpha skeletal muscle antibody ACTS_HUMAN antibody Alpha actin 1 antibody Alpha-actin-1 antibody ASMA antibody MPFD antibody AAT6 antibody ACTA_HUMAN antibody ACTA2 antibody Actin alpha 2 smooth muscle aorta antibody Actin aortic smooth muscle antibody Actin, aortic smooth muscle antibody ACTSA antibody ACTVS antibody Alpha 2 actin antibody Alpha actin 2 antibody Alpha cardiac actin antibody alpha sma antibody Alpha-actin-2 antibody Cell growth inhibiting gene 46 protein antibody Cell growth-inhibiting gene 46 protein antibody GIG46 antibody Growth inhibiting gene 46 antibody MYMY5 antibody ACTC antibody ACTC_HUMAN antibody ACTC1 antibody Actin alpha cardiac muscle 1 antibody Actin antibody alpha cardiac muscle 1 antibody Alpha-cardiac actin antibody ASD5 antibody CMD1R antibody CMH11 antibody LVNC4 antibody

Abbreviation

Actin, aortic smooth muscle, Alpha-actin-2,Cell growth-inhibiting gene 46 protein,ctin, aortic smooth muscle, intermediate form, ACTA2,Actin, alpha cardiac muscle 1,Alpha-cardiac actin,Actin, alpha cardiac muscle 1, intermediate form,ACTC1,Alpha-actin-1,Actin, alpha skeletal muscle,Actin, alpha skeletal muscle, intermediate form,ACTC

Swiss Prot

P68133 Human, P68032 Human, P62736 Human, P68134 Mouse, P68033 Mouse, P62737 Mouse, P68136 Rat, P68035 Rat, P62738 Rat

Cellular Locus

Cytoplasm, Cytoskeleton

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide corresponding to N terminal of Human Alpha actin (smooth muscle, skeletal muscle, cardiac muscle).

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

A431 cell lysate, MCF7 cell lysate, HEK-293 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, mouse smooth muscle tissue lysate, rat heart tissue lysate, HeLa, human heart tissue, human skeletal muscle tissue, mouse heart tissue, mouse skeletal muscle tissue, rat heart tissue, rat skeletal muscle tissue.

Concentration

2 mg/mL

Dilution

WB: 1:1,000 ;IHC-P: 1:10,000 ;IF-Cell: 1:100

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 42 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No