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Product details

MMAF Mouse Monoclonal Antibody [A5G11]

Catalog number HA600035

Price for HA600035

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Size / count 100 µL

About this product

Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of the approved drug belantamab mafodotin in multiple myeloma and some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. Monomethyl auristatin F is an antimitotic agent which inhibits cell division by blocking the polymerisation of tubulin. It is linked to an antibody with high affinity to structures on cancer cells, causing MMAF to accumulate in such cells. MMAF is actually desmethyl-auristatin F; that is, the N-terminal amino group has only one methyl substituent instead of two as in auristatin F itself.

Specifications

Catalog number
HA600035
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
MMAF antibody Monomethyl auristatin F antibdy
Host
Mouse
Species Reactivity
Universal
Immunogen
MMAF coupled with OVA.
Isotype
IgG1
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
ELISA
Concentration
2 mg/mL
Dilution
ELISA: 1:5,000-1:20,000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
PBS (pH7.4)
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for MMAF Mouse Monoclonal Antibody [A5G11]?

The catalog number for MMAF Mouse Monoclonal Antibody [A5G11] is HA600035.

What sizes are available for MMAF Mouse Monoclonal Antibody [A5G11]?

MMAF Mouse Monoclonal Antibody [A5G11] is available in the following size(s): 100 µL.

Is MMAF Mouse Monoclonal Antibody [A5G11] in stock?

MMAF Mouse Monoclonal Antibody [A5G11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is MMAF Mouse Monoclonal Antibody [A5G11] used for?

Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of the approved drug belantamab mafodotin in multiple myeloma and some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibod

Does this product need any special customs documentation to be imported to my country?

If you’re outside the EU, UK, or USA, you’re responsible for customs clearance and any related taxes or fees. We provide the standard import documents, such as the Commercial Invoice, Packing List, and Airway Bill, in advance, so let us know early if your customs office needs anything additional for this specific product.

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

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