Fibulin 5 Mouse Monoclonal Antibody [A1C12] — image 1 of 3

Product details

Fibulin 5 Mouse Monoclonal Antibody [A1C12]

Catalog number HA600044

Price for HA600044

Size / count 100 µL

About this product

Fibulin-5 (also known as DANCE (developmental arteries and neural crest epidermal growth factor (EGF)-like)) is a protein that in humans is encoded by the FBLN5 gene. The protein encoded by this gene is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling. FBLN5 has been shown to interact with LOXL1 and apolipoprotein (a). FBLN5 mutations have been described in patients with age-related macular degeneration, as well as being involved in Charcot-Marie-Tooth neuropathies.

Specifications

Catalog number: HA600044
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: ADCL2 antibody ARCL1A antibody ARMD3 antibody Dance antibody Developmental arteries and neural crest EGF like protein antibody Developmental arteries and neural crest EGF-like protein antibody EVEC antibody Fbln5 antibody FBLN5_HUMAN antibody FIBL 5 antibody FIBL-5 antibody Fibulin-5 antibody FLJ90059 antibody UP50 antibody Urine p50 protein antibody
Abbreviation: FBLN5
Swiss Prot: Q9UBX5 Human
Cellular Locus: Secreted, extracellular matrix.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within human Fibulin 5 aa 200-400.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, FC
Positive Control: A549 cell lysate, SKOV-3 cell lysate, Hela cell lysate, SiHa cell lysate, SiHa.
Concentration: 2 mg/mL
Dilution: WB:1:500-1:2,000 ;IF-Cell: 1:50-1:100 ;FC:1:100-1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 50 kDa (Predicted band size)
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

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