p47-phox Mouse Monoclonal Antibody [A6B11] — image 1 of 3

Product details

p47-phox Mouse Monoclonal Antibody [A6B11]

Catalog number HA600049

Price for HA600049

Size / count 100 µL

About this product

The heredity chronic granulomatous disease (CGF) has been linked to mutations in p47phox and p67-phox. The cytosolic proteins p47phox and p67-phox, also designated neutrophil cytosol factor (NCF)1 and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47phox and p67-phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47phox and p67-phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67-phox has been shown to interact with the proline-rich domain of p47phox, suggesting that p47phox may faciliate the transport of p67-phox to the membrane.

Specifications

Catalog number: HA600049
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 47 kDa autosomal chronic granulomatous disease protein antibody 47 kDa neutrophil oxidase factor antibody NADPH oxidase organizer 2 antibody NCF 47K antibody NCF-1 antibody NCF-47K antibody Ncf1 antibody NCF1_HUMAN antibody Neutrophil cytosol factor 1 antibody Neutrophil cytosolic factor 1 antibody neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) antibody Neutrophil NADPH oxidase factor 1 antibody Nox organizer 2 antibody Nox organizing protein 2 antibody Nox-organizing protein 2 antibody NOXO2 antibody p47 phox antibody p47-phox antibody SH3 and PX domain containing protein 1A antibody SH3 and PX domain-containing protein 1A antibody SH3PXD1A antibody
Abbreviation: NCF1, NOXO2, SH3PXD1A
Swiss Prot: P14598 Human, Q09014 Mouse
Cellular Locus: Cytoplasm, cytosol, Membrane.
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human p47-phox aa 51-250.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: Ramos cell lysate, Raji cell lysate, Daudi cell lysate, HL-60 cell lysate, Hela, NIH/3T3, human lung tissue, human spleen tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:2,000-1:5,000 ;IF-Cell: 1:50-1:200 ;IHC-P: 1:1,000
Purity: Protein G affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 45 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for p47-phox Mouse Monoclonal Antibody [A6B11]?

The catalog number for p47-phox Mouse Monoclonal Antibody [A6B11] is HA600049.

What sizes are available for p47-phox Mouse Monoclonal Antibody [A6B11]?

p47-phox Mouse Monoclonal Antibody [A6B11] is available in the following size(s): 100 µL.

Is p47-phox Mouse Monoclonal Antibody [A6B11] in stock?

p47-phox Mouse Monoclonal Antibody [A6B11] is currently made to order / not held in immediate stock. Contact us for lead time.

What is p47-phox Mouse Monoclonal Antibody [A6B11] used for?

What is the recommended positive control for this assay?

A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.

How should this product be stored?

Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.

Is this product animal-origin-free?

Animal-origin-free status, where applicable, is noted on the datasheet under formulation details.