p47-phox Mouse Monoclonal Antibody [A6B10] — image 1 of 3

Product details

p47-phox Mouse Monoclonal Antibody [A6B10]

Catalog number HA600050

Price for HA600050

Size / count 100 µL

About this product

The heredity chronic granulomatous disease (CGF) has been linked to mutations in p47phox and p67-phox. The cytosolic proteins p47phox and p67-phox, also designated neutrophil cytosol factor (NCF)1 and NCF2, respectively, are required for activation of the superoxide-producing NADPH oxidase in neutrophils and other phagocytic cells. During activation of the NADPH oxidase, p47phox and p67-phox migrate to the plasma membrane where they associate with cytochrome b558 and the small G protein Rac to form the functional enzyme complex. Both p47phox and p67-phox contain two Src homology 3 (SH3) domains. The C-terminal SH3 domain of p67-phox has been shown to interact with the proline-rich domain of p47phox, suggesting that p47phox may faciliate the transport of p67-phox to the membrane.

Specifications

Catalog number: HA600050
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: 47 kDa autosomal chronic granulomatous disease protein antibody 47 kDa neutrophil oxidase factor antibody NADPH oxidase organizer 2 antibody NCF 47K antibody NCF-1 antibody NCF-47K antibody Ncf1 antibody NCF1_HUMAN antibody Neutrophil cytosol factor 1 antibody Neutrophil cytosolic factor 1 antibody neutrophil cytosolic factor 1, (chronic granulomatous disease, autosomal 1) antibody Neutrophil NADPH oxidase factor 1 antibody Nox organizer 2 antibody Nox organizing protein 2 antibody Nox-organizing protein 2 antibody NOXO2 antibody p47 phox antibody p47-phox antibody SH3 and PX domain containing protein 1A antibody SH3 and PX domain-containing protein 1A antibody SH3PXD1A antibody
Abbreviation: NCF1
Swiss Prot: P14598 Human, Q09014 Mouse, F1M707 Rat
Cellular Locus: Cytosol, Membrane.
Host: Mouse
Species Reactivity: Human, Mouse
Immunogen: Recombinant protein within human p47-phox aa 51-250.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Raji cell lysates, Daudi cell lysates, Hela, NIH/3T3, human lung tissue, human spleen tissue, Daudi.
Concentration: 2 mg/mL
Dilution: WB: 1:2,000-1:5,000;IF-Cell: 1:50-1:200;IHC-P: 1:1,000-1:2,000;FC: 1:100
Purity: Protein G affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 45 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for p47-phox Mouse Monoclonal Antibody [A6B10]?

The catalog number for p47-phox Mouse Monoclonal Antibody [A6B10] is HA600050.

What sizes are available for p47-phox Mouse Monoclonal Antibody [A6B10]?

p47-phox Mouse Monoclonal Antibody [A6B10] is available in the following size(s): 100 µL.

Is p47-phox Mouse Monoclonal Antibody [A6B10] in stock?

p47-phox Mouse Monoclonal Antibody [A6B10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is p47-phox Mouse Monoclonal Antibody [A6B10] used for?

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.