eIF-6 Mouse Monoclonal Antibody [A6A2] — image 1 of 3

Product details

eIF-6 Mouse Monoclonal Antibody [A6A2]

Catalog number HA600052

Price for HA600052

Size / count 100 µL

About this product

Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)-dependent protein kinase C activity. In tissues responsive to insulin, controls fatty acid synthesis and glycolysis by exerting translational control of adipogenic transcription factors such as CEBPB, CEBPD and ATF4 that have G/C rich or uORF in their 5'UTR. Required for ROS-dependent megakaryocyte maturation and platelets formation, controls the expression of mitochondrial respiratory chain genes involved in reactive oxygen species (ROS) synthesis.

Specifications

Catalog number: HA600052
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: b (2)gcn antibody B (2)GCN homolog antibody B4 integrin interactor antibody Binding protein of beta-4 integrin antibody CAB antibody eIF-6 antibody EIF3A antibody EIF6 antibody Eukaryotic translation initiation factor 3A antibody Eukaryotic translation initiation factor 6 antibody IF6_HUMAN antibody Integrin beta 4 binding protein antibody ITGB4BP antibody OK/SW-cl.27 antibody p27 beta 4 integrin binding protein antibody p27 (BBP) antibody p27BBP antibody RP4-614O4.1 antibody
Abbreviation: EIF6
Swiss Prot: P56537 Human, O55135 Mouse, Q3KRD8 Rat
Cellular Locus: Cytoplasm, Nucleus, nucleolus.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human eIF-6 aa 1-200.
Isotype: IgG2a
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, IF-Cell, FC
Positive Control: HeLa cell lysate, HepG2 cell lysate, RAW264.7 cell lysate, NIH/3T3 cell lysate, mouse testis tissue lysate, rat kidney tissue lysate, rat testis tissue lysate, human colon cancer tissue, human kidney tissue, mouse kidney tissue, rat kidney tissue, HepG2, NIH/3T3.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:100 ;FC: 1:1,000
Purity: Protein G affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 27 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for eIF-6 Mouse Monoclonal Antibody [A6A2]?

The catalog number for eIF-6 Mouse Monoclonal Antibody [A6A2] is HA600052.

What sizes are available for eIF-6 Mouse Monoclonal Antibody [A6A2]?

eIF-6 Mouse Monoclonal Antibody [A6A2] is available in the following size(s): 100 µL.

Is eIF-6 Mouse Monoclonal Antibody [A6A2] in stock?

eIF-6 Mouse Monoclonal Antibody [A6A2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is eIF-6 Mouse Monoclonal Antibody [A6A2] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.