Glucosidase 2 subunit beta Mouse Monoclonal Antibody [A6H9]

About this product

Regulatory subunit of glucosidase II that cleaves sequentially the 2 innermost alpha-1,3-linked glucose residues from the Glc (2)Man (9)GlcNAc (2) oligosaccharide precursor of immature glycoproteins. Required for efficient PKD1/Polycystin-1 biogenesis and trafficking to the plasma membrane of the primary cilia (By similarity). This gene encodes the beta-subunit of glucosidase II, an N-linked glycan-processing enzyme in the endoplasmic reticulum. The encoded protein is an acidic phosphoprotein known to be a substrate for protein kinase C. Mutations in this gene have been associated with the autosomal dominant polycystic liver disease. Alternative splicing results in multiple transcript variants.

Specifications

Catalog number

HA600054

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

80K-H protein antibody AGE-binding receptor 2 antibody AGE-R2 antibody G19P1 antibody GLU2B_HUMAN antibody Glucosidase 2 subunit beta antibody Glucosidase II beta subunit antibody Glucosidase II subunit beta antibody Hepatocystin antibody PCLD antibody PKCSH antibody PLD1 antibody PRKCSH antibody Protein kinase C substrate 60.1 kDa protein heavy chain antibody Protein kinase C substrate 80 Kda protein antibody Protein kinase C substrate 80K-H antibody Protein kinase C substrate, 80 Kda protein antibody

Abbreviation

PRKCSH

Swiss Prot

P14314 Human

Cellular Locus

Endoplasmic reticulum.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within human Glucosidase 2 subunit beta aa 51-250.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

HeLa cell lysate, 293T cell lysate, Daudi cell lysate, Jurkat cell lysate, A431 cell lysate, Hela, human placenta tissue.

Concentration

2 mg/mL

Dilution

WB: 1:500-1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:200 ;FC: 1:500-1:1,000

Purity

Protein G affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 59 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No