LRP6 Mouse Monoclonal Antibody [A5E7] — image 1 of 2

Product details

LRP6 Mouse Monoclonal Antibody [A5E7]

Catalog number HA600065

Price for HA600065

Size / count 100 µL

About this product

Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Cell-surface coreceptor of Wnt/beta-catenin signaling, which plays a pivotal role in bone formation. The Wnt-induced Fzd/LRP6 coreceptor complex recruits DVL1 polymers to the plasma membrane which, in turn, recruits the AXIN1/GSK3B-complex to the cell surface promoting the formation of signalsomes and inhibiting AXIN1/GSK3-mediated phosphorylation and destruction of beta-catenin. Required for posterior patterning of the epiblast during gastrulation.

Specifications

Catalog number: HA600065
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: ADCAD2 antibody C030016K15Rik antibody Cd antibody FLJ90062 antibody FLJ90421 antibody LDL receptor related protein 6 antibody Low density lipoprotein receptor related protein 6 antibody Low-density lipoprotein receptor-related protein 6 antibody LRP-6 antibody LRP6 antibody LRP6_HUMAN antibody OTTHUMP00000238979 antibody OTTHUMP00000238980 antibody OTTHUMP00000238982 antibody STHAG7 antibody
Abbreviation: LRP6
Swiss Prot: O75581 Human
Cellular Locus: Endoplasmic reticulum, Cell membrane, Membrane raft.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within human LRP6 aa 100-300 / 1613.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Hela cell lysates, human colon tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 180 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for LRP6 Mouse Monoclonal Antibody [A5E7]?

The catalog number for LRP6 Mouse Monoclonal Antibody [A5E7] is HA600065.

What sizes are available for LRP6 Mouse Monoclonal Antibody [A5E7]?

LRP6 Mouse Monoclonal Antibody [A5E7] is available in the following size(s): 100 µL.

Is LRP6 Mouse Monoclonal Antibody [A5E7] in stock?

LRP6 Mouse Monoclonal Antibody [A5E7] is currently made to order / not held in immediate stock. Contact us for lead time.

What is LRP6 Mouse Monoclonal Antibody [A5E7] used for?

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

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