ACVR2B Mouse Monoclonal Antibody [A5H7]

Catalog number HA600067

Price for HA600067

Size / count 100 µL

About this product

Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. This gene encodes activin A type IIB receptor, which displays a 3- to 4-fold higher affinity for the ligand than activin A type II receptor.

Specifications

Catalog number: HA600067
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Activin A receptor type IIB antibody Activin receptor type 2B antibody Activin receptor type IIB antibody Activin receptor type-2B antibody ActR IIB antibody ACTR-IIB antibody ActRIIB antibody ACVR 2B antibody ACVR2B antibody AVR2B_HUMAN antibody HTX4 antibody MGC116908 antibody
Abbreviation: ACVR2B
Swiss Prot: Q13705 Human
Cellular Locus: Cell membrane.
Host: Mouse
Species Reactivity: Human, Mouse, Rat, Zebrafish
Immunogen: Synthetic peptide within human ACVR2B aa 331-380 / 512.
Isotype: IgG2a
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB
Positive Control: Hela cell lysates.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:2,000
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 58 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for ACVR2B Mouse Monoclonal Antibody [A5H7]?

The catalog number for ACVR2B Mouse Monoclonal Antibody [A5H7] is HA600067.

What sizes are available for ACVR2B Mouse Monoclonal Antibody [A5H7]?

ACVR2B Mouse Monoclonal Antibody [A5H7] is available in the following size(s): 100 µL.

Is ACVR2B Mouse Monoclonal Antibody [A5H7] in stock?

ACVR2B Mouse Monoclonal Antibody [A5H7] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ACVR2B Mouse Monoclonal Antibody [A5H7] used for?

How do I reconstitute this lyophilized product?

Reconstitution instructions, including the recommended diluent and final concentration, are provided on the datasheet. Aliquot immediately after reconstitution to avoid repeated freeze-thaw cycles.

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.