CENPB Mouse Monoclonal Antibody [A5F5] — image 1 of 3

Product details

CENPB Mouse Monoclonal Antibody [A5F5]

Catalog number HA600070

Price for HA600070

Size / count 100 µL

About this product

This gene product is a highly conserved protein that facilitates centromere formation. It is a DNA-binding protein that is derived from transposases of the pogo DNA transposon family. It contains a helix-loop-helix DNA binding motif at the N-terminus, and a dimerization domain at the C-terminus. The DNA binding domain recognizes and binds a 17-bp sequence (CENP-B box) in the centromeric alpha satellite DNA. This protein is proposed to play an important role in the assembly of specific centromere structures in interphase nuclei and on mitotic chromosomes. It is also considered a major centromere autoantigen recognized by sera from patients with anti-centromere antibodies.

Specifications

Catalog number: HA600070
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CENP B antibody CENP-B antibody CENPB antibody CENPB_HUMAN antibody centromere autoantigen B antibody Centromere protein B antibody Centromere protein B, 80kDa antibody Major centromere autoantigen B antibody
Abbreviation: CENPB
Swiss Prot: P07199 Human
Cellular Locus: Nucleus, centromere.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within human CENPB aa 1-200 / 599.
Isotype: IgG2a
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, IP
Positive Control: Hela cell lysate, A549 cell lysate, MCF-7 cell lysate, SK-OV-3, A549, human kidney tissue, human skin tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:400 ;IHC-P: 1:100-1:500 ;IP: Use at an assay dependent concentration.
Purity: Protein G affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 65 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CENPB Mouse Monoclonal Antibody [A5F5]?

The catalog number for CENPB Mouse Monoclonal Antibody [A5F5] is HA600070.

What sizes are available for CENPB Mouse Monoclonal Antibody [A5F5]?

CENPB Mouse Monoclonal Antibody [A5F5] is available in the following size(s): 100 µL.

Is CENPB Mouse Monoclonal Antibody [A5F5] in stock?

CENPB Mouse Monoclonal Antibody [A5F5] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CENPB Mouse Monoclonal Antibody [A5F5] used for?

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

Can I return this product if I ordered the wrong one?

As a consumer, you have a 14-day right of withdrawal from receipt under EU consumer protection law, submitted via our withdrawal/cancellation request form. Note this applies to unused, undamaged products, and doesn’t override the expiry/storage conditions on performance-based claims.

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.