RPS6 Mouse Monoclonal Antibody [A6B9]

About this product

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a cytoplasmic ribosomal protein that is a component of the 40S subunit. The protein belongs to the S6E family of ribosomal proteins. It is the major substrate of protein kinases in the ribosome, with subsets of five C-terminal serine residues phosphorylated by different protein kinases. Phosphorylation is induced by a wide range of stimuli, including growth factors, tumor-promoting agents, and mitogens. Dephosphorylation occurs at growth arrest. The protein may contribute to the control of cell growth and proliferation through the selective translation of particular classes of mRNA. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Specifications

Catalog number

HA600084

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

40S ribosomal protein S6 antibody Air8 antibody NP33 antibody Phosphoprotein NP33 antibody Pp30 antibody Ribosomal protein S6 antibody RP S6 antibody rps6 antibody RS6 antibody RS6_HUMAN antibody S6 antibody S6 Ribosomal Protein antibody

Abbreviation

RPS6

Swiss Prot

P62753 Human, P62754 Mouse, P62755 Rat

Cellular Locus

Cytosol, Endoplasmic reticulum, Nucleus.

Host

Mouse

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human RPS6 aa 1-150.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

HeLa cell lysate, MCF7 cell lysate, HepG2 cell lysate, HEK-293 cell lysate, HCT 116 cell lysate, THP-1 cell lysate, NIH/3T3 cell lysate, PC-12 cell lysate, human brain tissue lysate, human kidney tissue lysate, HeLa, human breast carcinoma tissue, human pancreas tissue, mouse colon tissue, rat brain tissue, rat hippocampus tissue.

Concentration

2 mg/mL

Dilution

WB: 1:500-1:2,000 ;IF-Cell: 1:200 ;IHC-P: 1:2,000 ;FC: 1:1,000

Purity

Protein G affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.2% BSA, 50% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 29 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No