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![Lamin A + Lamin C Mouse Monoclonal Antibody [A6F5] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8b061270361ea815e0/imageurl/ha600093.webp)
Product details
Catalog number HA600093
Price for HA600093
Size / count 100 µL
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated. Lamin proteins are thought to be involved in nuclear stability, chromatin structure and gene expression. Vertebrate lamins consist of two types, A and B. Alternative splicing results in multiple transcript variants. Mutations in this gene lead to several diseases: Emery-Dreifuss muscular dystrophy, familial partial lipodystrophy, limb girdle muscular dystrophy, dilated cardiomyopathy, Charcot-Marie-Tooth disease, and Hutchinson-Gilford progeria syndrome.
The catalog number for Lamin A + Lamin C Mouse Monoclonal Antibody [A6F5] is HA600093.
Lamin A + Lamin C Mouse Monoclonal Antibody [A6F5] is available in the following size(s): 100 µL.
Lamin A + Lamin C Mouse Monoclonal Antibody [A6F5] is currently made to order / not held in immediate stock. Contact us for lead time.
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated
A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
