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Product details

xCT/SLC7A11 Mouse Monoclonal Antibody [A7C6]

Catalog number HA600098

Price for HA600098

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Size / count 100 µL

About this product

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Specifications

Catalog number
HA600098
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Amino acid transport system xc xCT antibody antibody Amino acid transport system xc- antibody Calcium channel blocker resistance protein CCBR1 antibody Calcium channel blocker resistance protein CCBR1 antibody antibody CCBR1 antibody Cysteine/glutamate transporter antibody antibody Cystine/glutamate transporter antibody OTTHUMP00000164578 antibody SLC7A11 antibody Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 antibody solute carrier family 7 antibody Solute carrier family 7 member 11 antibody Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 antibody SYSTEM Xc (-) TRANSPORTER-RELATED PROTEIN antibody xCT antibody XCT_HUMAN antibody
Abbreviation
SLC7A11
Swiss Prot
Q9UPY5 Human, Q9WTR6 Mouse
Cellular Locus
Cell membrane, Cell projection, microvillus membrane.
Host
Mouse
Species Reactivity
Human, Mouse
Immunogen
293 cell line overexpressing SLC7A11.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
HT-29 cell lysates, HeLa, A549, HT-29, human colon tissue, human pancreas tissue.
Concentration
2 mg/mL
Dilution
WB: 1:500 ;IF-Cell: 1:100-1:250 ;IHC-P: 1:200-1:600 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for xCT/SLC7A11 Mouse Monoclonal Antibody [A7C6]?

The catalog number for xCT/SLC7A11 Mouse Monoclonal Antibody [A7C6] is HA600098.

What sizes are available for xCT/SLC7A11 Mouse Monoclonal Antibody [A7C6]?

xCT/SLC7A11 Mouse Monoclonal Antibody [A7C6] is available in the following size(s): 100 µL.

Is xCT/SLC7A11 Mouse Monoclonal Antibody [A7C6] in stock?

xCT/SLC7A11 Mouse Monoclonal Antibody [A7C6] is currently made to order / not held in immediate stock. Contact us for lead time.

What is xCT/SLC7A11 Mouse Monoclonal Antibody [A7C6] used for?

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the p

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

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