PDE4D Mouse Monoclonal Antibody [A7F3]

Catalog number HA601001

Price for HA601001

Size / count 100 µL

About this product

This gene encodes one of four mammalian counterparts to the fruit fly 'dunce' gene. cAMP-specific 3',5'-cyclic phosphodiesterase 4D is an enzyme that in humans is encoded by the PDE4D gene. The PDE4D gene is complex and has at least 9 different isoforms that encode functional proteins. These proteins degrade the second messenger cAMP, which is a key signal transduction molecule in multiple cell types, including vascular cells. PDE4D has been shown to interact with myomegalin and GNB2L1. Mutations in this gene have been associated to cases of acrodysostosis. This is the subtype of PDE4 that appears to be involved in the emetic and antidepressant effects of PDE4 inhibitors. Furthermore, changes in expression of the isoform PDE4D7 have been proposed as prostate cancer biomarker.

Specifications

Catalog number: HA601001
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: cAMP specific 3',5' cyclic phosphodiesterase 4D antibody DKFZp686M11213 antibody 5''-cyclic phosphodiesterase 4D antibody cAMP specific phosphodiesterase 4D antibody cAMP specific phosphodiesterase PDE4D6 antibody cAMP-specific 3'' antibody DPDE3 antibody Dunce like phosphodiesterase E3 antibody FLJ97311 antibody HSPDE4D antibody PDE43 antibody Pde4d antibody PDE4D_HUMAN antibody PDE4DN2 antibody Phosphodiesterase 4D cAMP specific (dunce (Drosophila) homolog phosphodiesterase E3) antibody Phosphodiesterase 4D cAMP specific (phosphodiesterase E3 dunce homolog Drosophila) antibody Phosphodiesterase 4D cAMP specific antibody Phosphodiesterase 4D, cAMP specific (dunce) antibody STRK1 antibody
Abbreviation: PDE4D
Swiss Prot: Q08499 Human
Cellular Locus: Apical cell membrane, Cytoplasm, Cytoskeleton, Centrosome, Membrane.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within Human PDE4D aa 610-809 / 809.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB
Positive Control: Hela cell lysates.
Concentration: 2 mg/mL
Dilution: WB: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 91 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for PDE4D Mouse Monoclonal Antibody [A7F3]?

The catalog number for PDE4D Mouse Monoclonal Antibody [A7F3] is HA601001.

What sizes are available for PDE4D Mouse Monoclonal Antibody [A7F3]?

PDE4D Mouse Monoclonal Antibody [A7F3] is available in the following size(s): 100 µL.

Is PDE4D Mouse Monoclonal Antibody [A7F3] in stock?

PDE4D Mouse Monoclonal Antibody [A7F3] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PDE4D Mouse Monoclonal Antibody [A7F3] used for?

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.