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Product details

Human IL-2 Mouse Monoclonal Antibody [A8B7] - BSA and Azide free (Detector)

Catalog number HA601006

Price for HA601006

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Size / count 100 µg

About this product

Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells. In the thymus, where T cells mature, it prevents autoimmune diseases by promoting the differentiation of certain immature T cells into regulatory T cells, which suppress other T cells that are otherwise primed to attack normal healthy cells in the body. IL-2 enhances activation-induced cell death (AICD). IL-2 also promotes the differentiation of T cells into effector T cells and into memory T cells when the initial T cell is also stimulated by an antigen, thus helping the body fight off infections. Together with other polarizing cytokines, IL-2 stimulates naive CD4+ T cell differentiation into Th1 and Th2 lymphocytes while it impedes differentiation into Th17 and folicular Th lymphocytes. IL-2 increases the cell killing activity of both natural killer cells and cytotoxic T cells. Its expression and secretion is tightly regulated and functions as part of both transient positive and negative feedback loops in mounting and dampening immune responses. Through its role in the development of T cell immunologic memory, which depends upon the expansion of the number and function of antigen-selected T cell clones, it plays a key role in enduring cell-mediated immunity. While the causes of itchiness are poorly understood, some evidence indicates that IL-2 is involved in itchy psoriasis.

Specifications

Catalog number
HA601006
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Aldesleukin antibody IL 2 antibody IL-2 antibody IL2 antibody IL2_HUMAN antibody Interleukin 2 antibody Interleukin-2 antibody interleukin2 antibody Involved in regulation of T cell clonal expansion antibody Lymphokine antibody OTTHUMP00000164090 antibody POIL2 antibody T Cell Growth Factor antibody T-cell growth factor antibody TCGF antibody
Abbreviation
IL2
Swiss Prot
P60568 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Recombinant protein within human IL-2 aa 1-153/153.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB, ELISA (Det)
Positive Control
IL-2 recombinant protein.
Concentration
2 mg/mL
Dilution
WB: 1:500 ;ELISA (Det): 1:5,000. Can be paired for Sandwich ELISA with Rabbit monoclonal [PSH01-42] to Human IL-2 (Capture) (HA721680).
Purity
Protein G affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 18 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for Human IL-2 Mouse Monoclonal Antibody [A8B7] - BSA and Azide free (Detector)?

The catalog number for Human IL-2 Mouse Monoclonal Antibody [A8B7] - BSA and Azide free (Detector) is HA601006.

What sizes are available for Human IL-2 Mouse Monoclonal Antibody [A8B7] - BSA and Azide free (Detector)?

Human IL-2 Mouse Monoclonal Antibody [A8B7] - BSA and Azide free (Detector) is available in the following size(s): 100 µg.

Is Human IL-2 Mouse Monoclonal Antibody [A8B7] - BSA and Azide free (Detector) in stock?

Human IL-2 Mouse Monoclonal Antibody [A8B7] - BSA and Azide free (Detector) is currently made to order / not held in immediate stock. Contact us for lead time.

What is Human IL-2 Mouse Monoclonal Antibody [A8B7] - BSA and Azide free (Detector) used for?

Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immun

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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