- Home
- Shop
- New Categories
- New Blog
- Contact Us
- Cart
- Login
- Register
![IL-2 Mouse Monoclonal Antibody [A8B8] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea81028/imageurl/ha601015.webp)
Product details
Catalog number HA601015
Price for HA601015
Size / count 100 µL
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immune system, tolerance and immunity, primarily via its direct effects on T cells. In the thymus, where T cells mature, it prevents autoimmune diseases by promoting the differentiation of certain immature T cells into regulatory T cells, which suppress other T cells that are otherwise primed to attack normal healthy cells in the body. IL-2 enhances activation-induced cell death (AICD). IL-2 also promotes the differentiation of T cells into effector T cells and into memory T cells when the initial T cell is also stimulated by an antigen, thus helping the body fight off infections. Together with other polarizing cytokines, IL-2 stimulates naive CD4+ T cell differentiation into Th1 and Th2 lymphocytes while it impedes differentiation into Th17 and folicular Th lymphocytes. IL-2 increases the cell killing activity of both natural killer cells and cytotoxic T cells. Its expression and secretion is tightly regulated and functions as part of both transient positive and negative feedback loops in mounting and dampening immune responses. Through its role in the development of T cell immunologic memory, which depends upon the expansion of the number and function of antigen-selected T cell clones, it plays a key role in enduring cell-mediated immunity. While the causes of itchiness are poorly understood, some evidence indicates that IL-2 is involved in itchy psoriasis.
The catalog number for IL-2 Mouse Monoclonal Antibody [A8B8] is HA601015.
IL-2 Mouse Monoclonal Antibody [A8B8] is available in the following size(s): 100 µL.
IL-2 Mouse Monoclonal Antibody [A8B8] is currently made to order / not held in immediate stock. Contact us for lead time.
Interleukin-2 (IL-2) is an interleukin, a type of cytokine signaling molecule in the immune system. It is a 15.5–16 kDa protein that regulates the activities of white blood cells (leukocytes, often lymphocytes) that are responsible for immunity. IL-2 has essential roles in key functions of the immun
Immunogen or antigen details used to raise this antibody are listed on the product datasheet under immunogen information.
A recommended positive control, where one is specified by the manufacturer, is listed on the datasheet or in the assay protocol.
Storage conditions depend on the specific reagent and are listed on the product datasheet, with most antibodies and proteins requiring -20°C unless stated otherwise. It is your responsibility to store the product correctly immediately upon receipt; damage from improper storage after delivery is not eligible for replacement.
