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Product details

IL-28A Mouse Monoclonal Antibody [A5D7]

Catalog number HA601026

Price for HA601026

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Size / count 100 µL

About this product

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the activation of the JAK/STAT signaling pathway resulting in the expression of IFN-stimulated genes (ISG), which mediate the antiviral state. Has a restricted receptor distribution and therefore restricted targets: is primarily active in epithelial cells and this cell type-selective action is because of the epithelial cell-specific expression of its receptor IFNLR1. Seems not to be essential for early virus-activated host defense in vaginal infection, but plays an important role in Toll-like receptor (TLR)-induced antiviral defense. Plays a significant role in the antiviral immune defense in the intestinal epithelium. Exerts an immunomodulatory effect by up-regulating MHC class I antigen expression.

Specifications

Catalog number
HA601026
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9007-83-4
Product Name Alternative
Cytokine ZCYTO20 antibody IFN-lambda-2 antibody IFNL2 antibody IL-28A antibody IL28A antibody IL28A_HUMAN antibody Interferon lambda 2 antibody Interferon lambda-2 antibody interleukin 28A (interferon, lambda 2) antibody Interleukin 28A antibody Interleukin-28A antibody ZCYTO20 antibody
Abbreviation
Interferon lambda-2 IFN-lambda-2 Cytokine Zcyto20 Interleukin-28A IL-28A
Swiss Prot
Q8IZJ0 Human
Cellular Locus
Secreted.
Host
Mouse
Species Reactivity
Human
Immunogen
Synthetic peptide within human IL28A aa 110-160.
Isotype
IgG2a
Conjugation
Non-conjugated
Type
Mouse monoclonal Antibody
Applications
WB
Positive Control
MCF-7 cell lysate, 293 cell lysate.
Concentration
2 mg/mL
Dilution
WB: 1:500-1:1,000
Purity
Protein G affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 22 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
No

Frequently Asked Questions

What is the catalog number for IL-28A Mouse Monoclonal Antibody [A5D7]?

The catalog number for IL-28A Mouse Monoclonal Antibody [A5D7] is HA601026.

What sizes are available for IL-28A Mouse Monoclonal Antibody [A5D7]?

IL-28A Mouse Monoclonal Antibody [A5D7] is available in the following size(s): 100 µL.

Is IL-28A Mouse Monoclonal Antibody [A5D7] in stock?

IL-28A Mouse Monoclonal Antibody [A5D7] is currently made to order / not held in immediate stock. Contact us for lead time.

What is IL-28A Mouse Monoclonal Antibody [A5D7] used for?

Cytokine with antiviral, antitumour and immunomodulatory activities. Plays a critical role in the antiviral host defense, predominantly in the epithelial tissues. Acts as a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IFNLR1, and receptor engagement leads to the act

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

What is the shelf life of this product?

Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.

What expression system was used for this recombinant protein?

The expression system, such as E. coli, HEK293, or insect cells, is listed on the datasheet under production details, which can affect post-translational modifications relevant to your application.

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