GM-CSF Mouse Monoclonal Antibody [A6C6] — image 1 of 2

Product details

GM-CSF Mouse Monoclonal Antibody [A6C6]

Catalog number HA601032

Price for HA601032

Size / count 100 µL

About this product

Granulocyte-macrophage colony-stimulating factor (GM-CSF), also known as colony-stimulating factor 2 (CSF2), is a monomeric glycoprotein secreted by macrophages, T cells, mast cells, natural killer cells, endothelial cells and fibroblasts that functions as a cytokine. Unlike granulocyte colony-stimulating factor, which specifically promotes neutrophil proliferation and maturation, GM-CSF affects more cell types, especially macrophages and eosinophils. GM-CSF is found in high levels in joints with rheumatoid arthritis and blocking GM-CSF as a biological target may reduce the inflammation or damage. Some drugs (e.g. otilimab) are being developed to block GM-CSF. In critically ill patients GM-CSF has been trialled as a therapy for the immunosuppression of critical illness, and has shown promise restoring monocyte and neutrophil function, although the impact on patient outcomes is currently unclear and awaits larger studies. GM-CSF stimulates monocytes and macrophages to produce pro-inflammatory cytokines, including CCL17. Elevated GM-CSF has been shown to contribute to inflammation in inflammatory arthritis, osteoarthritis, colitis asthma, obesity, and COVID-19.

Specifications

Catalog number: HA601032
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: Colony stimulating factor 2 (granulocyte-macrophage) antibody Colony Stimulating Factor 2 antibody Colony stimulating factor antibody Colony-stimulating factor antibody CSF 2 antibody CSF antibody CSF2 antibody CSF2_HUMAN antibody GM-CSF antibody GMCSF antibody Granulocyte Macrophage Colony Stimulating Factor antibody Granulocyte-macrophage colony-stimulating factor antibody MGC131935 antibody MGC138897 antibody MGI1GM antibody Molgramostin antibody Pluripoietin-a antibody Sargramostim antibody
Abbreviation: CSF2
Swiss Prot: P04141 Human
Cellular Locus: Secreted.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within Human GM-CSF aa 1-144/144.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, ELISA
Concentration: 2 mg/mL
Dilution: WB: 1:500 ;ELISA: 1:30,000
Purity: Protein G affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 16 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for GM-CSF Mouse Monoclonal Antibody [A6C6]?

The catalog number for GM-CSF Mouse Monoclonal Antibody [A6C6] is HA601032.

What sizes are available for GM-CSF Mouse Monoclonal Antibody [A6C6]?

GM-CSF Mouse Monoclonal Antibody [A6C6] is available in the following size(s): 100 µL.

Is GM-CSF Mouse Monoclonal Antibody [A6C6] in stock?

GM-CSF Mouse Monoclonal Antibody [A6C6] is currently made to order / not held in immediate stock. Contact us for lead time.

What is GM-CSF Mouse Monoclonal Antibody [A6C6] used for?

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.