Sall4 Mouse Monoclonal Antibody [A7A7]

About this product

Sal-like protein 4 (SALL4) is a transcription factor encoded by a member of the Spalt-like (SALL) gene family, SALL4. The SALL genes were identified based on their sequence homology to Spalt, which is a homeotic gene originally cloned in Drosophila melanogaster that is important for terminal trunk structure formation in embryogenesis and imaginal disc development in the larval stages. There are four human SALL proteins (SALL1, 2, 3, and 4) with structural homology and playing diverse roles in embryonic development, kidney function, and cancer. The SALL4 gene encodes at least three isoforms, termed A, B, and C, through alternative splicing, with the A and B forms being the most studied. SALL4 can alter gene expression changes through its interaction with many co-factors and epigenetic complexes. It is also known as a key embryonic stem cell (ESC) factor. The various SALL4-null mouse models mimic human mutations in the SALL4 gene, which were shown to cause developmental problems in patients with Okihiro/Duane-Radial-ray syndrome. These individuals frequently have family history of hand malformation and eye movement disorders.

Specifications

Catalog number

HA601042

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

AA407717 antibody AL022809 antibody AW536104 antibody C330011P20Rik antibody C78083 antibody C78563 antibody dJ1112F19.1 antibody DRRS antibody HSAL4 antibody Sal like 4 (Drosophila) antibody Sal like 4 antibody Sal like Protein 4 antibody Sal-like protein 4 antibody Sall4 antibody SALL4_HUMAN antibody Spalt like transcription factor 4 antibody Tex20 antibody Zinc finger protein 797 antibody Zinc finger protein SALL4 antibody ZNF797 antibody

Abbreviation

SALL4

Swiss Prot

Q9UJQ4 Human

Cellular Locus

Cytoplasm, Nucleus.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within human Sall4 aa 903-1,053/1,053

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC, IF-Tissue

Positive Control

NCCIT cell lysates, NCCIT, human seminoma tissue, human embryonal carcinoma tissue.

Concentration

2 mg/mL

Dilution

WB: 1:2,000 ;IF-Cell: 1:100 ;IHC-P: 1:600 ;FC: 1:500-1:10,000 ;IF-Tissue: 1:200

Purity

Protein G affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 112 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No