ROBO1 Recombinant Mouse Monoclonal Antibody [10E2-R]

Catalog number HA601056

Price for HA601056

Size / count 100 µL

About this product

Specific cells in the midline separate the left and right halves of the central nervous system and play many roles in guiding the growth cone behavior. In vertebrate spinal cord, insect abdominal nerves and nematodes, midline cells produce induced cues, such as nectins and slits, respectively, as attractants and repellents. respectively. These cells can serve as gatekeepers to prevent axons from passing through the midline and to guide the growth cone in response to the switching of lead cues beyond the crossing. One such gatherer, Robo, is an axon guidance receptor that defines a new subfamily of proteins from fruit flies to mammalian conserved Ig superfamily proteins. Robo acts as a receptor for the repellent Slit and functions in a cell-autonomous manner Non-intersecting axons express high levels of Robo and cross axons to express low levels of Robo and then reach midline and high levels of crossover. Robo1 and Robo2 are two human homologs of Drosophila megalopolis. Robo1 is also homologous to the C. elegans gene sax3, while Robo2 is homologous to zebrafish genes.

Specifications

Catalog number: HA601056
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Deleted in U twenty twenty antibody DUTT 1 antibody DUTT1 antibody FLJ21882 antibody H Robo 1 antibody H-Robo-1 antibody hRobo 1 antibody Robo 1 antibody Robo1 antibody ROBO1_HUMAN antibody Roundabout 1 antibody Roundabout axon guidance receptor homolog 1 antibody Roundabout homolog 1 antibody Roundabout homolog1 precurser antibody Roundabout1 antibody SAX 3 antibody SAX3 antibody
Abbreviation: Deleted in U twenty twenty,H-Robo-1,Roundabout homolog 1,ROBO1
Swiss Prot: Q9Y6N7 Human, O89026 Mouse, O55005 Rat
Cellular Locus: Cell membrane, Cell projection, axon, Endoplasmic reticulum-Golgi intermediate compartment membrane.
Host: Mouse
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within Human ROBO1 aa 51-300 / 1,651.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: MCF-7 cell lysate, NIH/3T3 cell lysate, rat brain tissue lysate, PC-12 cell lysate, RAW264.7 cell lysate, human breast tissue, human placenta tissue.
Concentration: 2 mg/mL
Dilution: WB: 1:1,000 ;IHC-P: 1:200-1:600
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 181 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for ROBO1 Recombinant Mouse Monoclonal Antibody [10E2-R]?

The catalog number for ROBO1 Recombinant Mouse Monoclonal Antibody [10E2-R] is HA601056.

What sizes are available for ROBO1 Recombinant Mouse Monoclonal Antibody [10E2-R]?

ROBO1 Recombinant Mouse Monoclonal Antibody [10E2-R] is available in the following size(s): 100 µL.

Is ROBO1 Recombinant Mouse Monoclonal Antibody [10E2-R] in stock?

ROBO1 Recombinant Mouse Monoclonal Antibody [10E2-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ROBO1 Recombinant Mouse Monoclonal Antibody [10E2-R] used for?

What do I do if this product arrives with reduced ice or a damaged cold-chain package?

Report this to us immediately with photos and your order reference. Our specialists will assess whether the product is still usable given the cold-chain interruption, and will arrange a replacement or credit if it isn’t.

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.