CD161 Mouse Monoclonal Antibody [A8E1]

Catalog number HA601063

Price for HA601063

Size / count 100 µL

About this product

Killer cell lectin-like receptor subfamily B, member 1, also known as KLRB1, NKR-P1A or CD161 (cluster of differentiation 161), is a human gene. Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein, NKR-P1A or CD161, is classified as a type II membrane protein because it has an external C terminus. NKR-P1A, the receptor encoded by the KLRB1 gene, recognizes Lectin Like Transcript-1 (LLT1) as a functional ligand. Expressed in a subset of NK cells predominantly in intestinal epithelium and liver. Detected in peripheral blood T-cells and preferentially in adult T-cells with a memory antigenic phenotype.

Specifications

Catalog number: HA601063
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: C-type lectin domain family 5 member B antibody CD161 antibody CLEC5B antibody HNKR-P1a antibody Killer Cell Lectin like Receptor Subfamily B Member 1 antibody Killer cell lectin-like receptor subfamily B member 1 antibody KLRB1 antibody KLRB1_HUMAN antibody Natural killer cell surface protein P1A antibody NKR antibody NKR P1 antibody NKR-P1A antibody NKRP1 antibody NKRP1A antibody
Abbreviation: Killer cell lectin-like receptor subfamily B member 1 C-type lectin domain family 5 member B HNKR-P1a NKR-P1A Natural killer cell surface protein P1A CD161 KLRB1 CLEC5B NKRP1A
Swiss Prot: Q12918 Human
Cellular Locus: Membrane
Host: Mouse
Species Reactivity: Human
Immunogen: Synthetic peptide within human CD161 aa 176-225.
Isotype: IgG2b
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: THP-1 cell lysate, HL-60 cell lysate, K-562 cell lysate, Jurkat cell lysate, human kidney tissue lysate, human kidney tissue, THP-1.
Concentration: 1.1 mg/mL
Dilution: WB: 1:2,000 ;IHC-P: 1:500 ;FC: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 25 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD161 Mouse Monoclonal Antibody [A8E1]?

The catalog number for CD161 Mouse Monoclonal Antibody [A8E1] is HA601063.

What sizes are available for CD161 Mouse Monoclonal Antibody [A8E1]?

CD161 Mouse Monoclonal Antibody [A8E1] is available in the following size(s): 100 µL.

Is CD161 Mouse Monoclonal Antibody [A8E1] in stock?

CD161 Mouse Monoclonal Antibody [A8E1] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD161 Mouse Monoclonal Antibody [A8E1] used for?

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.