Cytokeratin 7 Recombinant Mouse Monoclonal Antibody [3-G3-D8-R]

Catalog number HA601065

Price for HA601065

Size / count 100 µL

About this product

Keratin-7 is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. Keratin-7 is found in simple glandular epithelia, and in transitional epithelium. Epithelial cells of the lung and breast both contain keratin-7, but some other glandular epithelia, such as those of the colon and prostate, do not. Because the keratin-7 antigen is found in both healthy and neoplastic cells, antibodies to CK7 can be used in immunohistochemistry to distinguish ovarian and transitional cell carcinomas from colonic and prostate cancers, respectively. Pancreas is recommended as positive tissue control for CK7. Virtually all ductal and intercalated duct epithelial cells must show an at least weak to moderate, distinct cytoplasmic staining reaction, whereas epithelial cells of large ducts should display a strong staining intensity. Acinar epithelial cells should be negative. In general, no staining reaction should be seen in the epithelial cells. Scattered columnar epithelial cells and endothelial cells may show a weak to moderate cytoplasmic staining reaction.

Specifications

Catalog number: HA601065
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CK 7 antibody CK-7 antibody CK7 antibody Cytokeratin 7 antibody Cytokeratin-7 antibody D15Wsu77e antibody K2C7 antibody K2C7_HUMAN antibody K7 antibody Keratin 7 antibody Keratin 7, type II antibody Keratin type II cytoskeletal 7 antibody Keratin, 55K type II cytoskeletal antibody Keratin, simple epithelial antibody Keratin, simple epithelial type I, K7 antibody Keratin, type II cytoskeletal 7 antibody Keratin-7 antibody Krt2-7 antibody KRT7 antibody MGC11625 antibody MGC129731 antibody MGC3625 antibody Sarcolectin antibody SCL antibody Type II mesothelial keratin K7 antibody Type-II keratin Kb7 antibody Cytokeratin7
Abbreviation: CK-7,K7,K2C7
Swiss Prot: P08729 Human
Cellular Locus: Cytoplasm.
Host: Mouse
Species Reactivity: Human
Immunogen: Synthetic peptide within C-terminal human Cytokeratin 7.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: WB, IHC-P, FC
Positive Control: A549 cell lysate, HepG2 cell lysate, SKOV-3 cell lysate, Hela cell lysates, human breast tissue, human lung carcinoma tissue, Hela.
Concentration: 1 mg/mL
Dilution: WB: 1:1,000-1:5,000 ;IHC-P: 1:1,000-1:5,000 ;FC: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 51 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cytokeratin 7 Recombinant Mouse Monoclonal Antibody [3-G3-D8-R]?

The catalog number for Cytokeratin 7 Recombinant Mouse Monoclonal Antibody [3-G3-D8-R] is HA601065.

What sizes are available for Cytokeratin 7 Recombinant Mouse Monoclonal Antibody [3-G3-D8-R]?

Cytokeratin 7 Recombinant Mouse Monoclonal Antibody [3-G3-D8-R] is available in the following size(s): 100 µL.

Is Cytokeratin 7 Recombinant Mouse Monoclonal Antibody [3-G3-D8-R] in stock?

Cytokeratin 7 Recombinant Mouse Monoclonal Antibody [3-G3-D8-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 7 Recombinant Mouse Monoclonal Antibody [3-G3-D8-R] used for?

Is this product tested for endotoxin levels?

Endotoxin testing status is noted on the datasheet where applicable, particularly for recombinant proteins intended for cell-based or functional assays. If this isn’t listed and you need confirmation, contact support with the catalogue number.

Can I request additional validation data, such as western blot images, for this product?

Additional data may be available on request. Contact our technical support team with the catalogue number and we’ll check what supporting documentation the supplier can provide.

What documentation should I request if this product is used for a regulated or intellectual-property-sensitive application?

If the product is subject to intellectual property protections, we’ll advise on any MTA or usage restrictions before shipping. Let us know your intended end use so we can confirm what’s required upfront.