ACSL3 Mouse Monoclonal Antibody [A8F6]

About this product

Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL. Has mainly an anabolic role in energy metabolism. Mediates hepatic lipogenesis. Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates. Both isoforms exhibit the same level of activity (By similarity). The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene.

Specifications

Catalog number

HA601069

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9007-83-4

Product Name Alternative

ACS3 antibody Acsl3 antibody ACSL3_HUMAN antibody Acyl CoA synthetase long chain family member 3 antibody FACL3 antibody Fatty acid Coenzyme A ligase long chain 3 antibody LACS 3 antibody LACS3 antibody Lignoceroyl CoA synthase antibody Long chain acyl CoA synthetase 3 antibody Long chain fatty acid CoA ligase 3 antibody Long-chain acyl-CoA synthetase 3 antibody Long-chain-fatty-acid--CoA ligase 3 antibody PRO2194 antibody

Abbreviation

Fatty acid CoA ligase Acsl3 Arachidonate--CoA ligase Long-chain acyl-CoA synthetase 3 LACS 3 Long-chain-fatty-acid--CoA ligase 3 Medium-chain acyl-CoA ligase Acsl3 ACSL3 ACS3 FACL3 LACS3

Swiss Prot

O95573 Human

Cellular Locus

Mitochondrion, Peroxisome, Endoplasmic reticulum.

Host

Mouse

Species Reactivity

Human

Immunogen

Recombinant protein within human ACSL3 aa 180-380.

Isotype

IgG1

Conjugation

Non-conjugated

Type

Mouse monoclonal Antibody

Applications

WB

Positive Control

HeLa cell lysate, K-562 cell lysate, A431 cell lysate, 293T cell lysate.

Concentration

1.18 mg/mL

Dilution

WB: 1:1,000-1:5,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 80 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

No