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Product details

xCT/SLC7A11 Recombinant Mouse Monoclonal Antibody [A7C6-R]

Catalog number HA601071

Discontinued

Price for HA601071

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Size / count 100 µL

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About this product

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the predominant mediator of Kaposi sarcoma-associated herpesvirus fusion and entry permissiveness into cells. Also, increased expression of this gene in primary gliomas (compared to normal brain tissue) was associated with increased glutamate secretion via the XCT channels, resulting in neuronal cell death.

Specifications

Catalog number
HA601071
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
Yes
CAS Number
9000-83-3
Product Name Alternative
Amino acid transport system xc xCT antibody antibody Amino acid transport system xc- antibody Calcium channel blocker resistance protein CCBR1 antibody Calcium channel blocker resistance protein CCBR1 antibody antibody CCBR1 antibody Cysteine/glutamate transporter antibody antibody Cystine/glutamate transporter antibody OTTHUMP00000164578 antibody SLC7A11 antibody Solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 antibody solute carrier family 7 antibody Solute carrier family 7 member 11 antibody Solute carrier family 7, (cationic amino acid transporter, y+ system) member 11 antibody SYSTEM Xc (-) TRANSPORTER-RELATED PROTEIN antibody xCT antibody XCT_HUMAN antibody
Abbreviation
SLC7A11
Swiss Prot
Q9UPY5 Human, Q9WTR6 Mouse
Cellular Locus
Cell membrane, Cell projection, microvillus membrane.
Host
Mouse
Species Reactivity
Human, Mouse
Immunogen
293 cell line overexpressing SLC7A11.
Isotype
IgG2b
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
WB, IHC-P, IF-Cell, FC
Positive Control
HT-29 cell lysate, A549 cell lysate, HCT116 cell lysates, human pancreas tissue, HT-29, NIH/3T3 cell lysates.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:5,000 ;IHC-P: 1:200 ;IF-Cell: 1:100-1:200 ;FC: 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 55 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for xCT/SLC7A11 Recombinant Mouse Monoclonal Antibody [A7C6-R]?

The catalog number for xCT/SLC7A11 Recombinant Mouse Monoclonal Antibody [A7C6-R] is HA601071.

Is xCT/SLC7A11 Recombinant Mouse Monoclonal Antibody [A7C6-R] in stock?

xCT/SLC7A11 Recombinant Mouse Monoclonal Antibody [A7C6-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is xCT/SLC7A11 Recombinant Mouse Monoclonal Antibody [A7C6-R] used for?

This gene encodes a member of a heteromeric, sodium-independent, anionic amino acid transport system that is highly specific for cysteine and glutamate. In this system, designated Xc (-), the anionic form of cysteine is transported in exchange for glutamate. This protein has been identified as the p

Is this product classed as hazardous or restricted for shipping?

Some products are subject to special import/export regulations, dangerous goods handling, or licensing requirements. Where this applies, it’s noted on the product page, and any required extra documents or fees will be confirmed with you before dispatch, never added without your consent.

Can you help me confirm if this product is right for my specific experiment?

Yes, contact us with details of your sample type, species, and intended application, and our specialists will confirm suitability or suggest an alternative from our supplier network if this isn’t the best fit.

What is the purity of this recombinant protein?

Purity, typically assessed by SDS-PAGE, is listed on the datasheet under quality control data.

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