TSH Recombinant Mouse Monoclonal Antibody [AH21-10]

Catalog number HA601072

Price for HA601072

Size / count 100 µL

About this product

Thyroid-stimulating hormone (also known as TSH or thyrotropin) is a peptide hormone synthesized and secreted by thyrotrope cells in the anterior pituitary gland which regulate the endocrine function of the thyroid gland. TSH is a glycoprotein and consists of two subunits, the alpha and the beta subunit, which are non-covalently bound to one another. The alpha subunit of TSH is also present in two other pituitary glycoprotein hormones: Follicle stimulating hormone and luteinizing hormone and, in primates, in the placental hormone chorionic gonadotropin. Each of these hormones also has a unique beta subunit, which provides receptor specificity. In other words, TSH is composed of alpha subunit bound to the TSH beta subunit, and TSH associates only with its own receptor. Free alpha and beta subunits have essentially no biological activity. Anti-TSH reacts with TSH-producing cells (thyrotrophs), and is a useful marker in classification of pituitary tumors and the differential identification of primary and metastatic tumors in the pituitary gland.

Specifications

Catalog number: HA601072
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CG ALPHA antibody CGA antibody Chorionic gonadotropin alpha polypeptide antibody FSHA antibody Glycoprotein hormones alpha polypeptide antibody GPHA1 antibody Thyroid stimulating hormone beta subunit antibody Thyrotropin beta subunit antibody TSH beta antibody TSHA antibody TSHB antibody
Abbreviation: TSH-B, TSH-beta, TSHB
Swiss Prot: P01215 Human, P01222 Human
Cellular Locus: Secreted.
Host: Mouse
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within full length human TSH.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: IHC-P
Positive Control: Rat pituitary tissue, human placenta tissue.
Concentration: 1 mg/mL
Dilution: IHC-P: 1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 42 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for TSH Recombinant Mouse Monoclonal Antibody [AH21-10]?

The catalog number for TSH Recombinant Mouse Monoclonal Antibody [AH21-10] is HA601072.

What sizes are available for TSH Recombinant Mouse Monoclonal Antibody [AH21-10]?

TSH Recombinant Mouse Monoclonal Antibody [AH21-10] is available in the following size(s): 100 µL.

Is TSH Recombinant Mouse Monoclonal Antibody [AH21-10] in stock?

TSH Recombinant Mouse Monoclonal Antibody [AH21-10] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TSH Recombinant Mouse Monoclonal Antibody [AH21-10] used for?

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.

What should I do if I need to report a performance issue with a specific lot of this product?

Provide the catalogue number, product name, lot number, and your experimental results to our technical support team. They’ll investigate and, if needed, escalate to the manufacturer, provided the product was used before expiry and stored correctly.

What is the isotype of this antibody?

Isotype information such as IgG1 or IgG2a is listed in the product specifications on the datasheet, relevant for selecting compatible detection reagents.