Cytokeratin 20 Recombinant Mouse Monoclonal Antibody [A3H7-R]

Catalog number HA601077

Price for HA601077

Size / count 100 µL

About this product

The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. Keratin 20 is a type I cytokeratin. It is a major cellular protein of mature enterocytes and goblet cells and is specifically found in the gastric and intestinal mucosa. In immunohistochemistry, antibodies to CK20 can be used to identify a range of adenocarcinoma arising from epithelia that normally contain the CK20 protein. For example, the protein is commonly found in colorectal cancer, transitional cell carcinomas and in Merkel cell carcinoma, but is absent in lung cancer, prostate cancer, and non-mucinous ovarian cancer. It is often used in combination with antibodies to CK7 to distinguish different types of glandular tumour.

Specifications

Catalog number: HA601077
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CK 20 antibody CK-20 antibody CK20 antibody Cytokeratin-20 antibody Cytokeratin20 antibody K1C20_HUMAN antibody K20 antibody KA20 antibody Keratin 20 antibody keratin 20, type I antibody keratin 21, rat, homolog of antibody Keratin antibody Keratin type I cytoskeletal 20 antibody Keratin-20 antibody Keratin20 antibody KRT 20 antibody KRT 21 antibody KRT20 antibody KRT21 antibody MGC35423 antibody OTTHUMP00000164518 antibody Protein IT antibody type I cytoskeletal 20 antibody
Abbreviation: KRT20
Swiss Prot: P35900 Human
Cellular Locus: Cytoplasm.
Host: Mouse
Species Reactivity: Human
Immunogen: Synthetic peptide within C-terminal Human Cytokeratin 20.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: IHC-P
Positive Control: Human colon tissue, human small intestine tissue.
Concentration: 1 mg/mL
Dilution: IHC-P: 1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 48 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for Cytokeratin 20 Recombinant Mouse Monoclonal Antibody [A3H7-R]?

The catalog number for Cytokeratin 20 Recombinant Mouse Monoclonal Antibody [A3H7-R] is HA601077.

What sizes are available for Cytokeratin 20 Recombinant Mouse Monoclonal Antibody [A3H7-R]?

Cytokeratin 20 Recombinant Mouse Monoclonal Antibody [A3H7-R] is available in the following size(s): 100 µL.

Is Cytokeratin 20 Recombinant Mouse Monoclonal Antibody [A3H7-R] in stock?

Cytokeratin 20 Recombinant Mouse Monoclonal Antibody [A3H7-R] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Cytokeratin 20 Recombinant Mouse Monoclonal Antibody [A3H7-R] used for?

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.