CD204 Mouse Monoclonal Antibody [A8G2]

Catalog number HA601090

Price for HA601090

Size / count 100 µL

About this product

This gene encodes the class A macrophage scavenger receptors, which include three different types (1, 2, 3) generated by alternative splicing of this gene. These receptors or isoforms are macrophage-specific trimeric integral membrane glycoproteins and have been implicated in many macrophage-associated physiological and pathological processes including atherosclerosis, Alzheimer's disease, and host defense. The isoforms type 1 and type 2 are functional receptors and are able to mediate the endocytosis of modified low density lipoproteins (LDLs). The isoform type 3 does not internalize modified LDL (acetyl-LDL) despite having the domain shown to mediate this function in the types 1 and 2 isoforms. It has an altered intracellular processing and is trapped within the endoplasmic reticulum, making it unable to perform endocytosis. The isoform type 3 can inhibit the function of isoforms type 1 and type 2 when co-expressed, indicating a dominant negative effect and suggesting a mechanism for regulation of scavenger receptor activity in macrophages.

Specifications

Catalog number: HA601090
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9007-83-4
Product Name Alternative: CD204 antibody CD204 antigen antibody CD24 antibody Macrophage acetylated LDL receptor I and II antibody Macrophage scavenger receptor 1 antibody Macrophage scavenger receptor type III antibody Macrophage scavenger receptor types I and II antibody Msr 1 antibody MSR1 antibody MSRE_HUMAN antibody phSR1 antibody phSR2 antibody SCARA 1 antibody SCARA1 antibody Scavenger receptor class A member 1 antibody Scavenger receptor class A, member 1 antibody Scavenger receptor type A antibody Scvr antibody SR A antibody SRA antibody
Abbreviation: MSR1, SCARA1
Swiss Prot: P21757 Human
Cellular Locus: Membrane.
Host: Mouse
Species Reactivity: Human
Immunogen: Recombinant protein within Human CD204 aa 51-250 / 451.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Mouse monoclonal Antibody
Applications: WB, IHC-P
Positive Control: THP-1 cell lysate treated with 80nM PMA for 72 hours, human liver tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:5,000-1:10,000 ;IHC-P: 1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 50 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: No

Frequently Asked Questions

What is the catalog number for CD204 Mouse Monoclonal Antibody [A8G2]?

The catalog number for CD204 Mouse Monoclonal Antibody [A8G2] is HA601090.

What sizes are available for CD204 Mouse Monoclonal Antibody [A8G2]?

CD204 Mouse Monoclonal Antibody [A8G2] is available in the following size(s): 100 µL.

Is CD204 Mouse Monoclonal Antibody [A8G2] in stock?

CD204 Mouse Monoclonal Antibody [A8G2] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CD204 Mouse Monoclonal Antibody [A8G2] used for?

What is the recommended incubation time for this antibody?

A suggested incubation time is provided in the recommended protocol on the datasheet, but may need adjusting depending on your sample type and detection system.

What should I check when this product first arrives?

Inspect the package immediately for transportation damage, ice loss, leakage, or breakage. Report any issues right away with photos and your order reference; our specialists will determine whether the product is still usable or needs replacing.

Does this cell line or biologic require a Material Transfer Agreement (MTA)?

Some products, including certain cell lines, plasmids, and tissue cultures, are subject to intellectual property terms and may require an MTA before we can ship. We’ll inform you in advance if this product requires one, and additional handling fees may apply.