pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15]

Catalog number HA601094

Price for HA601094

Size / count 100 µL

About this product

Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. For example, cytokeratins 10 and 13 are expressed highly in a subset of squamous cell carcinomas while cytokeratin 18 is expressed in a majority of adenocarcinomas and basal cell carcinomas. Since each epithelium contains at least one acidic and one basic keratin, this antibody is used to observe the distribution of keratin-containing cells in normal epithelia and to identify neoplasms derived from such epithelium. Recognizes human cytokeratins 4, 5, 6, 8, 10, 13, and 18.

Specifications

Catalog number: HA601094
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: pan ck antibody pan-ck antibody panck antibody
Abbreviation: pan Cytokeratin
Swiss Prot: Q01546 Human, Q7Z794 Human
Cellular Locus: Cytoplasm.
Host: Mouse
Species Reactivity: Human
Immunogen: Recognizes human cytokeratins 4, 5, 6, 8, 10, 13, and 18.
Isotype: IgG1
Conjugation: Non-conjugated
Type: Recombinant Mouse monoclonal Antibody
Applications: IHC-P, IF-Cell, FC, mIHC
Positive Control: Human skin tissue, human breast tissue, human small intestine tissue, MCF-7, human pancreatic carcinoma.
Concentration: 1 mg/mL
Dilution: IHC-P: 1:500-1:1,000 ;IF-Cell: 1:50 ;FC: 1:500-1:1,000 ;mIHC: 1:3,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: PBS (pH7.4), 0.1% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15]?

The catalog number for pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15] is HA601094.

What sizes are available for pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15]?

pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15] is available in the following size(s): 100 µL.

Is pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15] in stock?

pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15] is currently made to order / not held in immediate stock. Contact us for lead time.

What is pan Cytokeratin Recombinant Mouse Monoclonal Antibody [PD00-15] used for?

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.