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![S100 beta Recombinant Mouse Monoclonal Antibody [PD00-11] — image 1 of 1](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80d4a/imageurl/ha601098.webp)
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Product details
Catalog number HA601098
Price for HA601098
Size / count 100 µL
S100 calcium binding protein B (S100 beta) is a member of the multifunctional S100 family of proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21; however, this gene is located at 21q22.3. S100 beta acts as a stimulator of proliferation and migration and as an inhibitor of apoptosis and differentiation in many cell types including astrocytes, Schwann cells, chondrocytes, adipocytes, certain neuronal populations, melanocytes, Langerhans cells, histiocytes, epithelial, and myoepithelial cells. This protein may function in Neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. Chromosomal rearrangements and altered expression of this gene have been implicated in several neurological, neoplastic, and other types of diseases, including Alzheimer's disease, Down's syndrome, epilepsy, amyotrophic lateral sclerosis, melanoma, and type I diabetes. S100 beta is also expressed in neoplasms derived from these cell types, making it a useful marker for the identification of melanoma and various nervous system tumors. Although ubiquitous, S100 beta has proven to be a sensitive marker for malignant melanoma, including desmoplastic and metastatic variants.
The catalog number for S100 beta Recombinant Mouse Monoclonal Antibody [PD00-11] is HA601098.
S100 beta Recombinant Mouse Monoclonal Antibody [PD00-11] is available in the following size(s): 100 µL.
S100 beta Recombinant Mouse Monoclonal Antibody [PD00-11] is currently made to order / not held in immediate stock. Contact us for lead time.
S100 calcium binding protein B (S100 beta) is a member of the multifunctional S100 family of proteins. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentia
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
Shelf life and expiration dates vary by product and are shown on the product listing and label. Products used beyond their expiration date are not eligible for performance-related returns or refunds, so please check the lot number and expiry before use.
