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Product details

HIV1 p24 Recombinant Mouse Monoclonal Antibody [12G4-R] - BSA and Azide free (Capture)

Catalog number HA601104

Price for HA601104

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Size / count 100 µg

About this product

One distinctive HIV antigen is a viral protein called p24, a structural protein that makes up most of the HIV viral core, or 'capsid'. There are approximately 2000 molecules per virus particle, or at a molecule weight of 24 kDa, about 104 virus particles per picogram of p24. The onset of symptoms of AIDS correlates with a reduction in the number of CD4+ T-cells and increased levels of virus and p24 in the blood. It is a component of the gag polyprotein. High levels of p24 are present in the blood serum of newly infected individuals during the short period between infection and seroconversion, making p24 antigen assays useful in diagnosing primary HIV infection. Antibodies to p24 are produced during seroconversion, rendering p24 antigen undetectable after seroconversion in most cases. Therefore, p24 antigen assays are not reliable for diagnosing HIV infection after its very earliest stages. Fourth-generation HIV immunoassays detect viral p24 protein in the blood (as well as patient antibodies against the virus). Previous generation tests relied on detecting patient antibodies alone; it takes about 3–4 weeks for the earliest antibodies to be detected. The p24 protein can be detected in patient blood as early as 2 weeks after HIV infection, further reducing the window period necessary to accurately detect the HIV status of the patient.

Specifications

Catalog number
HA601104
Size / count
100 µg
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CA antibody Capsid protein p24 antibody HIV-1 Gag p24 antibody HIV1gp1 antibody Human immunodeficiency virus 1 antibody Human immunodeficiency virus type 1 p24 antibody
Abbreviation
Gag p24 protein, gag p24
Swiss Prot
P12497 HIV1
Cellular Locus
Virion.
Host
Mouse
Species Reactivity
HIV-1
Immunogen
Recombinant protein within HIV1 p24 protein aa 133-363 (Catalog#HA210278).
Isotype
IgG1
Conjugation
Non-conjugated
Type
Recombinant Mouse monoclonal Antibody
Applications
ELISA (Cap)
Positive Control
Recombanint HIV1 p24 protein.
Concentration
1 mg/mL
Dilution
ELISA (Cap): 1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
PBS (pH7.4).
Molecular Weight
Predicted band size: 24 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for HIV1 p24 Recombinant Mouse Monoclonal Antibody [12G4-R] - BSA and Azide free (Capture)?

The catalog number for HIV1 p24 Recombinant Mouse Monoclonal Antibody [12G4-R] - BSA and Azide free (Capture) is HA601104.

What sizes are available for HIV1 p24 Recombinant Mouse Monoclonal Antibody [12G4-R] - BSA and Azide free (Capture)?

HIV1 p24 Recombinant Mouse Monoclonal Antibody [12G4-R] - BSA and Azide free (Capture) is available in the following size(s): 100 µg.

Is HIV1 p24 Recombinant Mouse Monoclonal Antibody [12G4-R] - BSA and Azide free (Capture) in stock?

HIV1 p24 Recombinant Mouse Monoclonal Antibody [12G4-R] - BSA and Azide free (Capture) is currently made to order / not held in immediate stock. Contact us for lead time.

What is HIV1 p24 Recombinant Mouse Monoclonal Antibody [12G4-R] - BSA and Azide free (Capture) used for?

One distinctive HIV antigen is a viral protein called p24, a structural protein that makes up most of the HIV viral core, or 'capsid'. There are approximately 2000 molecules per virus particle, or at a molecule weight of 24 kDa, about 104 virus particles per picogram of p24. The onset of symptoms of

How long will it take to receive this product if it’s custom made?

Lead times depend on the product type: custom polyclonal antibodies typically take 12-14 weeks, monoclonal antibodies 15-17 weeks, made-to-order recombinant proteins 4-8 weeks, and made-to-order recombinant antibodies 6-8 weeks. These are estimates and may shift due to production delays.

What is the recommended dilution for this antibody?

A recommended dilution range for each validated application is provided on the datasheet, but optimal dilution should be titrated for your specific experimental system, sample type, and detection method.

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

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