SNRPA1 Recombinant Rabbit Monoclonal Antibody [JE56-64]

About this product

U2 SnRNP A Antibody (B-3) is a high quality monoclonal U2 SnRNP A antibody (also designated U2 SnRNP A antibody) suitable for the detection of the U2 SnRNP A protein of mouse, rat and human origin. U2 SnRNP A Antibody (B-3) is available as both the non-conjugated anti-U2 SnRNP A antibody form, as well as multiple conjugated forms of anti-U2 SnRNP A antibody, including agarose, HRP, PE, FITC and multiple Alexa Fluor® conjugates. Small nuclear ribonucleoproteins, also known as snRNPs, combine with other proteins to form spliceosomes, a complex that catalyzes pre-mRNA splicing. There are two types of spliceosomes: U2 and U12. The U2-type spliceosome is found in all eukaryotes and excises U2-type introns, which account for the majority of pre-mRNA introns. The U12-type spliceosome removes U12-type introns, which comprise less than 1% of all human introns. U2 snRNP A, also known as SNRPA1 or U2A, is a component of the U2 snRNP that forms a complex with U2 snRNP B (U2B). Together, U2 snRNP A and U2 snRNP B form a complex that binds to the U2 snRNA hairpin IV. The configuration of this U2 snRNP A/U2 snRNP B dimer and the subtle variations of a few key residues regulate the snRNP-RNA-binding specificity. U2 snRNP A is a 255 amino acid protein, and two isoforms exist as a result of alternative splicing events.

Specifications

Catalog number

HA720019

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Lea1 antibody RU2A_HUMAN antibody Small nuclear ribonucleoprotein polypeptide A antibody SNRPA1 antibody U2 small nuclear ribonucleoprotein A'' antibody U2 small nuclear ribonucleoprotein polypeptide A' antibody U2 snRNP A antibody U2 snRNP A'' antibody

Abbreviation

SNRPA1

Swiss Prot

P09661 Human, P57784 Mouse

Cellular Locus

Nucleus.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human SNRPA1 aa 155-255.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P

Positive Control

Hela cell lysate, mouse liver tissue lysate, rat liver tissue lysate, Hela, SW620, rat testis tissue, rat cerebellum tissue, human cervix tissue, human prostate tissue, human breast carcinoma tissue, human kidney tissue, human placenta tissue, mouse brain tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:1,000;IF-Cell: 1:50-1:100;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

28 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes