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Product details

ZPR1 Recombinant Rabbit Monoclonal Antibody [JE58-88]

Catalog number HA720026

Price for HA720026

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Size / count 100 µL

About this product

The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene. Acts as a signaling molecule that communicates proliferative growth signals from the cytoplasm to the nucleus. Plays a role for the localization and accumulation of the survival motor neuron protein SMN1 in sub-nuclear bodies, including gems and Cajal bodies. Induces neuron differentiation and stimulates axonal growth and formation of growth cone in spinal cord motor neurons. Plays a role in the splicing of cellular pre-mRNAs. May be involved in H2O2-induced neuronal cell death.

Specifications

Catalog number
HA720026
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
MGC110983 antibody Zinc finger protein 259 antibody Zinc finger protein ZPR1 antibody ZNF 259 antibody ZNF259 antibody ZPR1 antibody ZPR1_HUMAN antibody
Abbreviation
ZPR1
Swiss Prot
O75312 Human, Q62384 Mouse
Cellular Locus
Nucleus, nucleolus, gem, Cajal body, perinuclear region, Cytoplasm, axon, growth cone.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Recombinant protein within human ZPR1 aa 360-459/459.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
HepG2 cell lysate, Jurkat cell lysate, human breast carcinoma tissue, mouse colon tissue, HepG2.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:1,000 ;IHC-P: 1:50-1:200 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 51 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for ZPR1 Recombinant Rabbit Monoclonal Antibody [JE58-88]?

The catalog number for ZPR1 Recombinant Rabbit Monoclonal Antibody [JE58-88] is HA720026.

What sizes are available for ZPR1 Recombinant Rabbit Monoclonal Antibody [JE58-88]?

ZPR1 Recombinant Rabbit Monoclonal Antibody [JE58-88] is available in the following size(s): 100 µL.

Is ZPR1 Recombinant Rabbit Monoclonal Antibody [JE58-88] in stock?

ZPR1 Recombinant Rabbit Monoclonal Antibody [JE58-88] is currently made to order / not held in immediate stock. Contact us for lead time.

What is ZPR1 Recombinant Rabbit Monoclonal Antibody [JE58-88] used for?

The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defec

What buffer is this product supplied in?

The formulation or storage buffer is listed on the product datasheet. If you require a carrier-free or custom formulation, contact us before ordering, as this may involve a made-to-order production timeline.

What dilution range is recommended for immunohistochemistry (IHC) with this antibody?

A starting IHC dilution range is listed on the datasheet, but should be optimized for your specific tissue type and staining protocol.

Can I request a Safety Data Sheet (SDS) for this product?

Yes, safety data sheets are available for hazardous or chemically classified products and can be provided on request or downloaded from the product page.

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