SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23] — image 1 of 3

Product details

SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23]

Catalog number HA720028

Price for HA720028

Size / count 100 µL

About this product

Signal recognition particle (SRP) is a ribonucleoprotein composed of an Alu domain and an S domain that contains six proteins. The S domain contains unique sequence SRP RNA and four SRP proteins: SRP19, SRP54, SRP68 and SRP72. The Alu domain contains two SRP proteins, SRP9 and SRP14. SRP interacts with ribosomes to bring translating membrane and secreted proteins to the endoplasmic reticulum (ER) for proper processing. SRP9 and SRP14 form a heterodimer before binding to SRP RNA, and SRP19 functions in the assembly of SRP and binds to free SRP RNA. This event is a prerequisite for the subsequent binding of SRP54 to helix 8 of SRP RNA in eukaryotes and involves an SRP19-induced conformational change in the RNA. SRP54 interacts with both the nascent signal peptide and SRP RNA. SRP68 binding to SRP RNA enhances SRP72 binding. SRP19, SRP68 and SRP72 are localized in the nucleolus and cytoplasm, whereas SRP54 is only localized in the cytoplasm. SRP68 also accumulates in the ER. Thus, the nucleolus is the site of assembly and/or interaction between the family of ribonucleoproteins involved in protein synthesis.

Specifications

Catalog number: HA720028
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Signal recognition particle 19 kDa protein antibody signal recognition particle 19kDa antibody SRP19 antibody SRP19_HUMAN antibody
Abbreviation: SRP19
Swiss Prot: P09132 Human, Q9D7A6 Mouse
Cellular Locus: Cytoplasm.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein within human SRP19 aa 1-100/144.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IHC-P
Positive Control: Jurkat cell lysate, Hela cell lysate, HepG2 cell lysate, rat brain tissue lysate, rat kidney tissue lysate, mouse stomach tissue lysate, rat large intestine tissue, human colon carcinoma tissue, human skin tissue.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 16 kDa.
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23]?

The catalog number for SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23] is HA720028.

What sizes are available for SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23]?

SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23] is available in the following size(s): 100 µL.

Is SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23] in stock?

SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23] is currently made to order / not held in immediate stock. Contact us for lead time.

What is SRP19 Recombinant Rabbit Monoclonal Antibody [JE59-23] used for?

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.