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Product details

TUB Recombinant Rabbit Monoclonal Antibody [JE58-75]

Catalog number HA720035

Price for HA720035

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Size / count 100 µL

About this product

This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Functions in signal transduction from heterotrimeric G protein-coupled receptors. Binds to membranes containing phosphatidylinositol 4,5-bisphosphate. Can bind DNA (in vitro). May contribute to the regulation of transcription in the nucleus. Could be involved in the hypothalamic regulation of body weight (By similarity). Contribute to stimulation of phagocytosis of apoptotic retinal pigment epithelium (RPE) cells and macrophages.

Specifications

Catalog number
HA720035
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
F10B5.4 antibody rd5 antibody TUB 1 antibody TUB antibody TUB_HUMAN antibody Tubby homologue antibody Tubby protein homolog 1 antibody Tubby protein homolog antibody
Abbreviation
TUB
Swiss Prot
P50607 Human, P50586 Mouse
Cellular Locus
Secreted, Cell membrane, Nucleus, Cytoplasm.
Host
Rabbit
Species Reactivity
Human, Mouse
Immunogen
Synthetic peptide within human TUB aa 1-50/506.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P, FC
Positive Control
SH-SY5Y cell lysates, mouse brain tissue, SH-SY5Y.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;FC: 1:500-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 56 kDa.
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for TUB Recombinant Rabbit Monoclonal Antibody [JE58-75]?

The catalog number for TUB Recombinant Rabbit Monoclonal Antibody [JE58-75] is HA720035.

What sizes are available for TUB Recombinant Rabbit Monoclonal Antibody [JE58-75]?

TUB Recombinant Rabbit Monoclonal Antibody [JE58-75] is available in the following size(s): 100 µL.

Is TUB Recombinant Rabbit Monoclonal Antibody [JE58-75] in stock?

TUB Recombinant Rabbit Monoclonal Antibody [JE58-75] is currently made to order / not held in immediate stock. Contact us for lead time.

What is TUB Recombinant Rabbit Monoclonal Antibody [JE58-75] used for?

This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

What temperature does this product ship at?

Shipping temperature is chosen based on the product’s stability needs, ranging from ambient to dry ice, and is indicated on the product page. Any related shipping fee is shown clearly in your quotation.

What is the molecular weight of the target protein?

Molecular weight information, where applicable, is listed on the datasheet under target details, useful for confirming the correct band on western blot.

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