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![p40-phox Recombinant Rabbit Monoclonal Antibody [JE58-57] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8a061270361ea80fa9/imageurl/ha720040.webp)
Product details
Catalog number HA720040
Price for HA720040
Size / count 100 µL
The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation. This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system. The PX domain of this protein can bind phospholipid products of the PI (3) kinase, which suggests its role in PI (3) kinase-mediated signaling events. The phosphorylation of this protein was found to negatively regulate the enzyme activity. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
The catalog number for p40-phox Recombinant Rabbit Monoclonal Antibody [JE58-57] is HA720040.
p40-phox Recombinant Rabbit Monoclonal Antibody [JE58-57] is available in the following size(s): 100 µL.
p40-phox Recombinant Rabbit Monoclonal Antibody [JE58-57] is currently made to order / not held in immediate stock. Contact us for lead time.
The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense. This protein is preferentially expressed in cells of myeloid lineage. It interacts primarily with neutrophil cytosolic
Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.
Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.
Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.
