FDFT1 Recombinant Rabbit Monoclonal Antibody [JE60-69]

About this product

Several proteins mediate the biosynthesis of cholesterol. The first specific step in the cholesterol biosynthetic pathway is the conversion of transfarnesyl-diphosphate to Squalene, which is catalyzed by the endoplasmic reticulum membrane-associated enzyme Squalene synthetase, also designated Squalene synthase and Farnesyl-diphosphate farnesyltransferase. Squalene synthetase is located at a branch point in the mevalonate pathway and is also involved in isoprenoid biosynthesis. Squalene epoxidase, also designated Squalene monooxygenase, is a multi-pass microsomal membrane-associated enzyme that catalyzes the first oxygenation step in sterol biosynthesis and most likely functions as one of the rate-limiting enzymes in this pathway. Squalene epoxidase may form a complex with Squalene synthetase.

Specifications

Catalog number

HA720048

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

DGPT antibody ERG9 antibody Farnesyl diphosphate farnesyltransferase antibody Farnesyl-diphosphate farnesyltransferase antibody FDFT_HUMAN antibody FDFT1 antibody FPP:FPP farnesyltransferase antibody SQS antibody Squalene synthase antibody Squalene synthetase antibody SS antibody

Abbreviation

FDFT1

Swiss Prot

P37268 Human, P53798 Mouse, Q02769 Rat

Cellular Locus

Endoplasmic reticulum membrane.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human FDFT1 aa 101-300/417.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P, IF-Cell

Positive Control

HepG2 cell lysate, rat kidney tissue lysate, SH-SY5Y cell lysate, mouse brain tissue lysate, rat liver tissue, human liver tissue, human liver carcinoma tissue, SH-SY5Y.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200 ;IF-Cell: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 48 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes