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![GBP1 Recombinant Rabbit Monoclonal Antibody [JE60-78] — image 1 of 2](https://cdn.genprice.uk/products/992/68dd1c90061270361ea82898/imageurl/ha720049.webp)
Product details
Catalog number HA720049
Price for HA720049
Size / count 100 µL
GBP1 (guanylate binding protein 1) is a 592 amino acid protein member of the GTPase protein family and is able to bind specifically to guanine nucleotides such as GMP, GDP and GTP. GMP is hydrolyzed to GTP in two consecutive cleavage steps, both of which are carried out by GBP1. Localized to the cytoplasm, GBP1 is expressed in endothelial cells of the vascular system and is induced by INF-γ during macrophage induction. GBP1 is thought to regulate the expression of MMP-1, which mediates the proliferation and invasiveness of endothelial cells. GBP1 plays a key role in regulating inflammatory cytokines and provides protection against vesicular stomatitis and encephalomyocarditis viruses. GBP1 expression is highly induced in the vessels of skin diseases such as psoriasis and Kaposi′s sarcoma, making it a novel cellular activation marker that characterizes inflammatory cytokines of endothelial cells.
The catalog number for GBP1 Recombinant Rabbit Monoclonal Antibody [JE60-78] is HA720049.
GBP1 Recombinant Rabbit Monoclonal Antibody [JE60-78] is available in the following size(s): 100 µL.
GBP1 Recombinant Rabbit Monoclonal Antibody [JE60-78] is currently made to order / not held in immediate stock. Contact us for lead time.
GBP1 (guanylate binding protein 1) is a 592 amino acid protein member of the GTPase protein family and is able to bind specifically to guanine nucleotides such as GMP, GDP and GTP. GMP is hydrolyzed to GTP in two consecutive cleavage steps, both of which are carried out by GBP1. Localized to the cyt
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.
