Collagen III Recombinant Rabbit Monoclonal Antibody [JE60-79]

About this product

Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of ADGRG1 in the developing brain and binding to ADGRG1 inhibits neuronal migration and activates the RhoA pathway by coupling ADGRG1 to GNA13 and possibly GNA12. This gene encodes the pro-alpha1 chains of type III collagen, a fibrillar collagen that is found in extensible connective tissues such as skin, lung, uterus, intestine and the vascular system, frequently in association with type I collagen. Mutations in this gene are associated with Ehlers-Danlos syndrome types IV, and with aortic and arterial aneurysms. Two transcripts, resulting from the use of alternate polyadenylation signals, have been identified for this gene.

Specifications

Catalog number

HA720050

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Alpha 1 type III collagen antibody Alpha1 (III) collagen antibody CO3A1_HUMAN antibody COL 3A1 antibody COL3A1 antibody Collagen alpha 1 (III) chain antibody Collagen alpha-1 (III) chain antibody Collagen III alpha 1 chain precursor antibody Collagen III alpha 1 polypeptide antibody Collagen type III alpha 1 (Ehlers Danlos syndrome type IV autosomal dominant) antibody Collagen type III alpha 1 antibody Collagen type III alpha 1 chain antibody Collagen type III alpha antibody Collagen, fetal antibody EDS4A antibody Ehlers Danlos syndrome type IV, autosomal dominant antibody Fetal collagen antibody Type III collagen antibody

Abbreviation

COL3A1

Swiss Prot

P02461 Human, P08121 Mouse, P13941 Rat

Cellular Locus

Extracellular matrix.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Recombinant protein within human Collagen III 101-400/1,466.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, FC

Positive Control

HeLa cell lysate, A431 cell lysate, SiHa cell lysate, HaCaT cell lysate, NIH/3T3 cell lysate, RAW264.7 cell lysate, C6 cell lysate, PC-12 cell lysate, Mouse heart tissue lysate, Mouse skin tissue lysate, Mouse skeletal muscle tissue lysate, Rat skeletal muscle tissue lysate, Rat skin tissue lysate, SiHa, HeLa.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IF-Cell: 1:50-1:100 ;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 139 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes