PPP6C Recombinant Rabbit Monoclonal Antibody [JE61-21]

About this product

In eukaryotes, the phosphorylation and dephosphorylation of proteins on serine and threonine residues is an essential means of regulating a broad range of cellular functions including division, homeostasis and apoptosis. A group of proteins that are intimately involved in this process are the protein phosphatases. In general, the protein phosphatase (PP) holoenzyme is a trimeric complex composed of a regulatory subunit, a variable subunit and a catalytic subunit. Four major families of protein phosphatase catalytic subunit have been identified, designated PP1, PP2A, PP2B and PP2C. An additional protein phosphatase catalytic subunit, PPX, is a putative member of a novel PP family. PP6, also known as PPP6C, is a 305 amino acid cytoplasmic protein that belongs to the PPP phosphatase family. Ubiquitously expressed, PP6 is component of a signaling pathway regulating cell cycle progression in response to IL-2 receptor stimulation and is involved in suppressing inflammatory responses by specifically down-regulating TR4.

Specifications

Catalog number

HA720056

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

FLJ92648 antibody MGC12249 antibody PP 6 antibody PP6 antibody PP6C antibody PPP 6 antibody PPP 6C antibody PPP6 antibody PPP6_HUMAN antibody Ppp6c antibody Protein phosphatase 6 catalytic subunit antibody Serine/threonine protein phosphatase 6 antibody Serine/threonine protein phosphatase catalytic subunit antibody Serine/threonine-protein phosphatase 6 catalytic subunit antibody

Abbreviation

PPP6C

Swiss Prot

O00743 Human, Q9CQR6 Mouse

Cellular Locus

Mitochondrion, Cytoplasm.

Host

Rabbit

Species Reactivity

Human, Mouse

Immunogen

Synthetic peptide within human PPP6C aa 255-305/305.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IF-Cell, IHC-P, FC

Positive Control

Hela cell lysate, mouse spleen tissue lysate, human kidney tissue, Hela, SiHa.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000;IF-Cell: 1:50;IHC-P: 1:50-1:100;FC: 1:500-1:1,000

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

35 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes