CHM Recombinant Rabbit Monoclonal Antibody [JE61-83] — image 1 of 3

Product details

CHM Recombinant Rabbit Monoclonal Antibody [JE61-83]

Catalog number HA720064

Price for HA720064

Size / count 100 µL

About this product

This gene encodes component A of the RAB geranylgeranyl transferase holoenzyme. In the dimeric holoenzyme, this subunit binds unprenylated Rab GTPases and then presents them to the catalytic Rab GGTase subunit for the geranylgeranyl transfer reaction. Rab GTPases need to be geranylgeranyled on either one or two cysteine residues in their C-terminus to localize to the correct intracellular membrane. Mutations in this gene are a cause of choroideremia; also known as tapetochoroidal dystrophy (TCD). This X-linked disease is characterized by progressive dystrophy of the choroid, retinal pigment epithelium and retina. Alternatively spliced transcript variants have been found for this gene. Besides, a pre-formed complex consisting of CHM and the Rab GGTase dimer (RGGT or component B) can bind to and prenylate Rab proteins; this alternative pathway is proposed to be the predominant pathway for Rab protein geranylgeranylation.

Specifications

Catalog number: HA720064
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: CHM antibody Chm antibody Choroideraemia protein antibody Choroideremia antibody DXS540 antibody FLJ38564 antibody GGTA antibody HSD 32 antibody MGC102710 antibody Rab escort protein 1 antibody Rab geranylgeranyltransferase component A antibody Rab proteins geranylgeranyltransferase component A 1 antibody RAE1_HUMAN antibody REP 1 antibody REP-1 antibody REP1 antibody TCD antibody TCD protein antibody
Abbreviation: CHM
Swiss Prot: P24386 Human, Q9QXG2 Mouse, P37727 Rat
Cellular Locus: Cytosol.
Host: Rabbit
Species Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide within human CHM aa 36-85/653.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P, FC
Positive Control: Mouse colon tissue lysates, human colon carcinoma tissue, human endometrium tissue, rat rectum tissue, SiHa, Hela.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000;IF-Cell: 1:50;IHC-P: 1:50-1:200;FC: 1:500-1:1,000
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: 73 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for CHM Recombinant Rabbit Monoclonal Antibody [JE61-83]?

The catalog number for CHM Recombinant Rabbit Monoclonal Antibody [JE61-83] is HA720064.

What sizes are available for CHM Recombinant Rabbit Monoclonal Antibody [JE61-83]?

CHM Recombinant Rabbit Monoclonal Antibody [JE61-83] is available in the following size(s): 100 µL.

Is CHM Recombinant Rabbit Monoclonal Antibody [JE61-83] in stock?

CHM Recombinant Rabbit Monoclonal Antibody [JE61-83] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CHM Recombinant Rabbit Monoclonal Antibody [JE61-83] used for?

Can I get a trial-size or discounted first order of this product?

We don’t generally offer free samples, but trial discounts in exchange for feedback and validation results are almost always possible. Contact us with your intended application to arrange one.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.