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Product details

Mitofusin 2 Recombinant Rabbit Monoclonal Antibody [JE59-66]

Catalog number HA720073

Price for HA720073

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Size / count 100 µL

About this product

Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Membrane clustering requires GTPase activity and may involve a major rearrangement of the coiled coil domains. Plays a central role in mitochondrial metabolism and may be associated with obesity and/or apoptosis processes. Plays an important role in the regulation of vascular smooth muscle cell proliferation. Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy). Is required for PRKN recruitment to dysfunctional mitochondria. Involved in the control of unfolded protein response (UPR) upon ER stress including activation of apoptosis and autophagy during ER stress. Acts as an upstream regulator of EIF2AK3 and suppresses EIF2AK3 activation under basal conditions.

Specifications

Catalog number
HA720073
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
CMT2A antibody CMT2A2 antibody CPRP 1 antibody CPRP1 antibody EC 3.6.5.- antibody Fzo antibody HSG antibody hyperplasia suppressor gene antibody Hypertension related protein 1 antibody KIAA0214 antibody MARF antibody MFN 2 antibody Mfn2 antibody MFN2_HUMAN antibody Mitochondrial assembly regulatory factor antibody Mitofusin-2 antibody Mitofusin2 antibody Transmembrane GTPase MFN2 antibody
Abbreviation
MFN2
Swiss Prot
O95140 Human, Q8R500 Rat
Cellular Locus
Mitochondrion outer membrane.
Host
Rabbit
Species Reactivity
Human, Rat
Immunogen
Synthetic peptide within human Mitofusin 2 aa 51-100/757.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
Rat brain tissue lysate, 293 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 86 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for Mitofusin 2 Recombinant Rabbit Monoclonal Antibody [JE59-66]?

The catalog number for Mitofusin 2 Recombinant Rabbit Monoclonal Antibody [JE59-66] is HA720073.

What sizes are available for Mitofusin 2 Recombinant Rabbit Monoclonal Antibody [JE59-66]?

Mitofusin 2 Recombinant Rabbit Monoclonal Antibody [JE59-66] is available in the following size(s): 100 µL.

Is Mitofusin 2 Recombinant Rabbit Monoclonal Antibody [JE59-66] in stock?

Mitofusin 2 Recombinant Rabbit Monoclonal Antibody [JE59-66] is currently made to order / not held in immediate stock. Contact us for lead time.

What is Mitofusin 2 Recombinant Rabbit Monoclonal Antibody [JE59-66] used for?

Mitochondrial outer membrane GTPase that mediates mitochondrial clustering and fusion. Mitochondria are highly dynamic organelles, and their morphology is determined by the equilibrium between mitochondrial fusion and fission events. Overexpression induces the formation of mitochondrial networks. Me

What host species was used to raise this antibody?

The host species used in production is listed under product specifications on the datasheet, and is relevant when selecting a compatible secondary antibody for your assay.

What is the difference between this product and a similar catalogue number?

Differences typically involve clone, conjugate, host species, or validated applications. Compare the respective datasheets, or contact us with both catalogue numbers for a direct comparison.

Do you offer custom or private-label production of this type of product?

Yes, custom antibody development and private-label production services are available. Contact our sales team to discuss your target, timeline, and quantity requirements.

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