HMGCS2 Recombinant Rabbit Monoclonal Antibody [JE54-76]

About this product

3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) is an enzyme in humans that is encoded by the HMGCS2 gene. The protein encoded by this gene belongs to the HMG-CoA synthase family. It is a mitochondrial enzyme that catalyzes the second and rate-limiting reaction of ketogenesis, a metabolic pathway that provides lipid-derived energy for various organs during times of carbohydrate deprivation, such as fasting, by addition of a third acetyl group to acetoacetyl-CoA, producing HMG-CoA. Mutations in this gene are associated with HMG-CoA synthase deficiency. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Specifications

Catalog number

HA720083

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 (mitochondrial) antibody 3 hydroxy 3 methylglutaryl Coenzyme A synthase 2 antibody 3 hydroxy 3 methylglutaryl coenzyme A synthase antibody 3-hydroxy-3-methylglutaryl coenzyme A synthase antibody HMCS2_HUMAN antibody HMG CoA synthase antibody HMG-CoA synthase antibody HMGCS 2 antibody HMGCS2 antibody Hydroxymethylglutaryl CoA synthase antibody Hydroxymethylglutaryl CoA synthase mitochondrial antibody Hydroxymethylglutaryl-CoA synthase antibody mitochondrial antibody

Abbreviation

HMGCS2

Swiss Prot

P54868 Human, P54869 Mouse, P22791 Rat

Cellular Locus

Mitochondrion.

Host

Rabbit

Species Reactivity

Human, Mouse, Rat

Immunogen

Synthetic peptide within human HMGCS2 aa 459-508/508.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

Caco-2 cell lysate, mouse kidney tissue lysate, rat kidney tissue lysate, rat liver tissue, human kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:2,000 ;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 1%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 57 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes