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![Cystatin-B Recombinant Rabbit Monoclonal Antibody [JE63-34] — image 1 of 3](https://cdn.genprice.uk/products/992/68dd1c8c061270361ea81d5c/imageurl/ha720084.webp)
Product details
Catalog number HA720084
Price for HA720084
Size / count 100 µL
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and kininogens. This gene encodes a stefin that functions as an intracellular thiol protease inhibitor. The protein is able to form a dimer stabilized by noncovalent forces, inhibiting papain and cathepsins l, h and b. The protein is thought to play a role in protecting against the proteases leaking from lysosomes. Evidence indicates that mutations in this gene are responsible for the primary defects in patients with progressive myoclonic epilepsy (EPM1). One type of mutation responsible for EPM1 is the expansion in the promoter region of this gene of a CCCCGCCCCGCG repeat from 2-3 copies to 30-78 copies.
The catalog number for Cystatin-B Recombinant Rabbit Monoclonal Antibody [JE63-34] is HA720084.
Cystatin-B Recombinant Rabbit Monoclonal Antibody [JE63-34] is available in the following size(s): 100 µL.
Cystatin-B Recombinant Rabbit Monoclonal Antibody [JE63-34] is currently made to order / not held in immediate stock. Contact us for lead time.
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the t
A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.
Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.
Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.
