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Product details

AMSH Recombinant Rabbit Monoclonal Antibody [JE63-41]

Catalog number HA720085

Price for HA720085

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Size / count 100 µL

About this product

Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) signaling by antagonizing the inhibitory action of SMAD6 and SMAD7. Has a key role in regulation of cell surface receptor-mediated endocytosis and ubiquitin-dependent sorting of receptors to lysosomes. Endosomal localization of STAMBP is required for efficient EGFR degradation but not for its internalization (By similarity). Involved in the negative regulation of PI3K-AKT-mTOR and RAS-MAP signaling pathways.

Specifications

Catalog number
HA720085
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
AMSH antibody Associated molecule with the SH3 domain of STAM antibody Endosome associated ubiquitin isopeptidase antibody Endosome-associated ubiquitin isopeptidase antibody MGC126516 antibody MGC126518 antibody MICCAP antibody STABP_HUMAN antibody STAM binding protein antibody STAM-binding protein antibody Stambp antibody
Abbreviation
STAMBP
Swiss Prot
O95630 Human
Cellular Locus
Cytoplasm, Endosome, Membrane, Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human AMSH aa 151-200/424.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB
Positive Control
MCF-7 cell lysate, 293T cell lysate, HepG2 cell lysate, Hela cell lysate, SW480 cell lysate.
Concentration
1 mg/mL
Dilution
WB: 1:500
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 48 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for AMSH Recombinant Rabbit Monoclonal Antibody [JE63-41]?

The catalog number for AMSH Recombinant Rabbit Monoclonal Antibody [JE63-41] is HA720085.

What sizes are available for AMSH Recombinant Rabbit Monoclonal Antibody [JE63-41]?

AMSH Recombinant Rabbit Monoclonal Antibody [JE63-41] is available in the following size(s): 100 µL.

Is AMSH Recombinant Rabbit Monoclonal Antibody [JE63-41] in stock?

AMSH Recombinant Rabbit Monoclonal Antibody [JE63-41] is currently made to order / not held in immediate stock. Contact us for lead time.

What is AMSH Recombinant Rabbit Monoclonal Antibody [JE63-41] used for?

Zinc metalloprotease that specifically cleaves 'Lys-63'-linked polyubiquitin chains. Does not cleave 'Lys-48'-linked polyubiquitin chains (By similarity). Plays a role in signal transduction for cell growth and MYC induction mediated by IL-2 and GM-CSF. Potentiates BMP (bone morphogenetic protein) s

What is the recommended storage temperature after reconstitution?

Post-reconstitution storage guidance is listed on the datasheet, typically requiring aliquoting and storage at -20°C or -80°C to preserve activity.

Can this product be used in multiplex assays?

Multiplex compatibility depends on the specific product and detection panel. Contact our technical support team with details of your multiplex system for guidance before ordering.

What happens if this product doesn’t perform as expected in my experiment?

Send us the catalogue number, product name, lot number, and a summary of your results. Our technical support team will investigate and, where needed, involve the manufacturer. This is covered under our guarantee provided the product was used before its expiry date and stored correctly.

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