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Product details

CCDC98 Recombinant Rabbit Monoclonal Antibody [JE62-73]

Catalog number HA720094

Price for HA720094

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Size / count 100 µL

About this product

This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint control. Pseudogenes of this gene are found on chromosomes 3 and 8. Alternative splicing results in multiple transcript variants. Component of the BRCA1-A complex, acting as a central scaffold protein that assembles the various components of the complex and mediates the recruitment of BRCA1. The BRCA1-A complex specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesion sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at DSBs. This complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX.

Specifications

Catalog number
HA720094
Size / count
100 µL
Dry ice
No
Hazardous
No
Discontinued
No
CAS Number
9000-83-3
Product Name Alternative
3830405G04Rik antibody 5630400M01Rik antibody ABRA1 antibody ABRAXAS antibody Abraxas protein antibody AI506069 antibody AL024423 antibody AV118690 antibody BRCA1-A complex subunit Abraxas antibody coiled coil domain containing 98 antibody Coiled-coil domain-containing protein 98 antibody F175A_HUMAN antibody FAM175A antibody Family with sequence similarity 175 member A antibody FLJ11520 antibody FLJ12642 antibody FLJ13614 antibody Protein FAM175A antibody
Abbreviation
ABRAXAS1
Swiss Prot
Q6UWZ7 Human
Cellular Locus
Nucleus.
Host
Rabbit
Species Reactivity
Human
Immunogen
Synthetic peptide within human CCDC98 aa 360-409/409.
Isotype
IgG
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IF-Cell, IHC-P, FC
Positive Control
K562 cell lysate, Daudi cell lysate, HL-60 cell lysate, SH-SY5Y, human rectum tissue, human tonsil tissue, SiHa.
Concentration
1 mg/mL
Dilution
WB: 1:500-1:2,000;IF-Cell: 1:50-1:100;IHC-P: 1:100-1:500;FC: 1:50-1:100
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 47 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes

Frequently Asked Questions

What is the catalog number for CCDC98 Recombinant Rabbit Monoclonal Antibody [JE62-73]?

The catalog number for CCDC98 Recombinant Rabbit Monoclonal Antibody [JE62-73] is HA720094.

What sizes are available for CCDC98 Recombinant Rabbit Monoclonal Antibody [JE62-73]?

CCDC98 Recombinant Rabbit Monoclonal Antibody [JE62-73] is available in the following size(s): 100 µL.

Is CCDC98 Recombinant Rabbit Monoclonal Antibody [JE62-73] in stock?

CCDC98 Recombinant Rabbit Monoclonal Antibody [JE62-73] is currently made to order / not held in immediate stock. Contact us for lead time.

What is CCDC98 Recombinant Rabbit Monoclonal Antibody [JE62-73] used for?

This gene encodes a protein that binds to the C-terminal repeats of breast cancer 1 (BRCA1) through a phospho-SXXF motif. The encoded protein recruits ubiquitin interaction motif containing 1 protein to BRCA1 protein and is required for DNA damage resistance, DNA repair, and cell cycle checkpoint co

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

Is this product covered by a money-back guarantee?

Yes, we guarantee a full refund or store credit if this product arrives damaged beyond usability, or has a genuine performance issue under proper usage and storage, provided you report it immediately with evidence. Claims after the expiration date or due to improper storage after receipt are excluded.

Can this product be used for diagnostic or therapeutic purposes?

No. This product, like all items we supply, is intended for research laboratory use only and must not be used for diagnostics, therapeutics, treatment, or consumption by humans or animals.

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