Kallikrein 8 Recombinant Rabbit Monoclonal Antibody [JE62-46]

About this product

Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury. Expressed at high levels in serum, ascites fluid and tumor cytosol of advanced stage ovarian cancer patients and may serve as a marker of ovarian cancer. Cleavage of amide substrates following the basic amino acids Arg or Lys at the P1 position, with a preference for Arg over Lys. Inhibited by a range of serine protease inhibitors including antipain, aprotinin, leupeptin, benzamidine and soybean trypsin inhibitor.

Specifications

Catalog number

HA720101

Size / count

100 µL

Dry ice

No

Hazardous

No

Discontinued

No

CAS Number

9000-83-3

Product Name Alternative

Brain serine protease 1 antibody BSP1 antibody hK8 antibody HNP antibody HPN antibody Kallikrein 8 (neuropsin/ovasin) antibody Kallikrein related peptidase 8 antibody Kallikrein-8 antibody Kallikrein8 antibody KLK 8 antibody Klk8 antibody KLK8 protein type 1 antibody KLK8 protein type 2 antibody KLK8_HUMAN antibody Neuropsin antibody neuropsin type 1 antibody Neuropsin type 1, included antibody Neuropsin type 2 antibody Neuropsin type 2, included antibody Neuropsin, mouse, homolog of antibody NP antibody NRPN antibody Ovasin antibody PRO322 antibody Protease serine 19 antibody PRSS 19 antibody PRSS19 antibody Serine protease 19 antibody Serine protease kallikrein antibody Serine protease kallikrein/ovasin/neuropsin antibody Serine protease TADG 14 antibody Serine protease TADG-14 antibody Serine protease TADG14 antibody TADG 14 antibody TADG14 antibody Tumor associated differentially expressed gene 14 antibody Tumor associated differentially expressed gene 14 protein antibody Tumor-associated differentially expressed gene 14 protein antibody UNQ283 antibody

Abbreviation

KLK8

Swiss Prot

O60259 Human

Cellular Locus

Secreted, Cytoplasm.

Host

Rabbit

Species Reactivity

Human

Immunogen

Recombinant protein within human Kallikrein 8 aa 161-260/260.

Isotype

IgG

Conjugation

Non-conjugated

Type

Recombinant Rabbit monoclonal Antibody

Applications

WB, IHC-P

Positive Control

A431 cell lysate, Jurkat cell lysate, Hela cell lysate, human kidney tissue.

Concentration

1 mg/mL

Dilution

WB: 1:500-1:2,000 ;IHC-P: 1:50-1:200

Purity

Protein A affinity purified.

Form

Liquid

Buffer

1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.

Molecular Weight

Predicted band size: 28 kDa

Storage Conditions

Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.

Recombinant Antibody

Yes