PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44] — image 1 of 3

Product details

PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44]

Catalog number HA720102

Price for HA720102

Size / count 100 µL

About this product

PKC-related serine/threonine-protein kinase and Rho/Rac effector protein that participates in specific signal transduction responses in the cell. Plays a role in the regulation of cell cycle progression, actin cytoskeleton assembly, cell migration, cell adhesion, tumor cell invasion and transcription activation signaling processes. Phosphorylates CTTN in hyaluronan-induced astrocytes and hence decreases CTTN ability to associate with filamentous actin. Phosphorylates HDAC5, therefore lead to impair HDAC5 import. Direct RhoA target required for the regulation of the maturation of primordial junctions into apical junction formation in bronchial epithelial cells. Required for G2/M phases of the cell cycle progression and abscission during cytokinesis in a ECT2-dependent manner. Stimulates FYN kinase activity that is required for establishment of skin cell-cell adhesion during keratinocytes differentiation. Regulates epithelial bladder cells speed and direction of movement during cell migration and tumor cell invasion. Inhibits Akt pro-survival-induced kinase activity. Mediates Rho protein-induced transcriptional activation via the c-fos serum response factor (SRF). Involved in the negative regulation of ciliogenesis.

Specifications

Catalog number: HA720102
Size / count: 100 µL
Dry ice: No
Hazardous: No
Discontinued: No
CAS Number: 9000-83-3
Product Name Alternative: Cardiolipin activated protein kinase Pak2 antibody MGC150606 antibody MGC71074 antibody PAK 2 antibody PAK2 antibody PKN gamma antibody PKN2 antibody PKN2_HUMAN antibody PRK2 antibody PRKCL2 antibody PRO2042 antibody Protein kinase C like 2 antibody Protein kinase C related kinase 2 antibody Protein kinase C-like 2 antibody Protein kinase N2 antibody Protein-kinase C-related kinase 2 antibody Serine/threonine-protein kinase N2 antibody
Abbreviation: PKN2
Swiss Prot: Q16513 Human, O08874 Rat
Cellular Locus: Cytoskeleton, Nucleus, Cytoplasm, Membrane, lamellipodium, Cleavage furrow, Midbody, Cell junction.
Host: Rabbit
Species Reactivity: Human, Rat
Immunogen: Recombinant protein within human PKN2 aa 885-984/984.
Isotype: IgG
Conjugation: Non-conjugated
Type: Recombinant Rabbit monoclonal Antibody
Applications: WB, IF-Cell, IHC-P
Positive Control: A431 cell lysate, rat lung tissue lysate, rat bladder tissue, SiHa.
Concentration: 1 mg/mL
Dilution: WB: 1:500-1:2,000 ;IF-Cell: 1:50 ;IHC-P: 1:100-1:500
Purity: Protein A affinity purified.
Form: Liquid
Buffer: 1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight: Predicted band size: 112 kDa
Storage Conditions: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody: Yes

Frequently Asked Questions

What is the catalog number for PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44]?

The catalog number for PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44] is HA720102.

What sizes are available for PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44]?

PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44] is available in the following size(s): 100 µL.

Is PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44] in stock?

PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44] is currently made to order / not held in immediate stock. Contact us for lead time.

What is PKN2 Recombinant Rabbit Monoclonal Antibody [JE62-44] used for?

Is this antibody conjugated?

Conjugation status, such as unconjugated, HRP, FITC, or biotin, is specified in the product name and confirmed on the datasheet.

What is the sensitivity of this ELISA kit?

Assay sensitivity, including the minimum detectable dose, is listed on the datasheet. Kits that are assembled on order typically ship within 2-4 weeks.

Do you ship this product with dry ice?

Some products, including certain cell lines and biologics, require dry ice for transportation, which carries an additional fee shown clearly in your quotation. Dry ice delivery isn’t always possible to every destination due to transit time or local restrictions, so we check feasibility in advance and you must store the goods at the correct temperature the moment they arrive.